Gene therapy cures boy of sickle cell disease
New Scientist - 01-Mar-2017People with sickle cell disease make abnormal versions of haemoglobin – distorting red blood cell...
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Professor of Gene Medicine at the University of Oxford.
Deborah Gill is based in the John Radcliffe Hospital in Oxford where she is Professor of Gene Medicine, Co-Director of the Gene Medicine Research Group and Head of the Nuffield Division of Clinical Laboratory Sciences within the Radcliffe Department of Medicine at the University of Oxford.
Deborah completed her PhD in molecular microbiology at the University of Warwick, studying cell division proteins in E.coli, during which she discovered the defining bacterial member of the ABC (ATP-Binding Cassette) superfamily of proteins. Deborah then moved to the University of Oxford, to undertake post-doctoral research at the Weatherall Institute for Molecular Medicine, investigating human ABC proteins including the Multi-Drug Resistance p-glycoprotein and CFTR, the protein responsible for Cystic Fibrosis (CF). Deborah's research then began to focus on the potential of gene therapy for genetic diseases, developing a potential treatment for Cystic Fibrosis lung disease, and resulting in multiple clinical trials demonstrating proof of principle for CF gene therapy.
Visit website: https://www.rdm.ox.ac.uk/people/deborah-gill
See also: University of Oxford - Collegiate research university and one of the world's leading universities
Details last updated 24-Dec-2020
People with sickle cell disease make abnormal versions of haemoglobin – distorting red blood cell...