Dr. Soto is a professor of neurology and director of the Mitchell Center for Alzheimer’s Disease and Related Brain Disorders at The University of Texas Health Science Center at Houston. He has worked on neurodegenerative diseases — with a focus on Alzheimer’s disease, Parkinson’s disease and diseases related to protein misfolding — for the past 28 years and has made important discoveries that contribute to understanding these disorders and to the development of novel strategies for treatment and early diagnosis.

He invented and developed Protein Misfolding Cyclic Amplification (PMCA, also known as RT-QuIC) for ultra-sensitive detection of misfolded proteins. Dr. Soto has published >190 peer review papers, which have been cited over 16,000 times (H index 67). Forty-five of the articles have more than 100 citations and 3 have more than 800. He is ranked 6 in the U.S. among PIs of NIH-funded research studies in neurology, according to the Blue Ridge Institute.