Scientists uncover the secret behind cancer cell's immortality
Medical Xpress - 10-Sep-2018Doesn't seem to harm normal cells unlike telomerase blocking drugs that are too toxic
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Research Scientist at Genentech
I study the effects of the protein, GABPβ1L, on regulation of the mutant TERT promoter, and its impact on cell immortality. I am exploring a therapeutic approach in glioblastoma patient-derived cell cultures to specifically target the mutant TERT promoter, which should limit effects on non-cancerous cells.
- Eight years of research experience in molecular biology and functional genomics
- Expertise in NGS assay development and optimization, as well as NGS data generation, including sample preparation, library generation, and operating Illumina sequencers
- Expertise in SNP biology, genetic regulatory mechanisms, and pre-clinical experiments
- High impact publication record: Cancer Cell; Journal of Neuro-Oncology; Molecular Cancer Research
Visit website: https://costellolab.ucsf.edu/people/ana-xavier-magalhaes
See also: Genentech - Company creating and delivering innovative medicines.
Details last updated 19-Apr-2020
Doesn't seem to harm normal cells unlike telomerase blocking drugs that are too toxic