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Ana Xavier-Magalhaes

Research Scientist at Genentech

I study the effects of the protein, GABPβ1L, on regulation of the mutant TERT promoter, and its impact on cell immortality. I am exploring a therapeutic approach in glioblastoma patient-derived cell cultures to specifically target the mutant TERT promoter, which should limit effects on non-cancerous cells.

- Eight years of research experience in molecular biology and functional genomics

- Expertise in NGS assay development and optimization, as well as NGS data generation, including sample preparation, library generation, and operating Illumina sequencers

- Expertise in SNP biology, genetic regulatory mechanisms, and pre-clinical experiments

- High impact publication record: Cancer Cell; Journal of Neuro-Oncology; Molecular Cancer Research


Visit website: https://costellolab.ucsf.edu/people/ana-xavier-magalhaes

 anaxaviermagalhaes

See also: Company Genentech - Company creating and delivering innovative medicines.

Details last updated 19-Apr-2020

Ana Xavier-Magalhaes News

Scientists uncover the secret behind cancer cell's immortality

Scientists uncover the secret behind cancer cell's immortality

Medical Xpress - 10-Sep-2018

Doesn't seem to harm normal cells unlike telomerase blocking drugs that are too toxic