He is a physician scientist who performs basic, translational, and clinical research focused on diseases related to metabolism (e.g. metabolic syndrome, obesity, non-alcoholic fatty liver disease, atherosclerosis, and type 2 diabetes. His laboratory investigates the intersection of circadian rhythms, gut signaling, and the microbiome and how the three together can underlie a variety of pathological conditions. By using engineered bacteria and time restricted feeding, we hope to understand how to prevent and treat these conditions. He is also a practicing gastroenterologist at VA San Diego where he directs the bariatric endoscopy clinic and perform research investigating how to use precision medicine to improve weight loss and non-alcoholic liver disease outcomes. Finally, he is a dedicated mentor, striving to help young scientists achieve their career goals.