A quick summary of projects trying to recreate cells, tissues and organs in silico
Virtual 3D models of the body and individual organs will allow us to test drugs and procedures faster than ever before with no harm to patients or animals.
Clinical trials (i.e. testing a drug in humans) can take years to perform - going through phase 1 (checking for safety), phase 2 (checking for efficacy and side-effects) and phase 3 (monitoring adverse reactions). Less than one in ten successfully make it to market. That's a lot of wasted time and effort.
Digital modelling allows testing from a cellular level to whole body interactions to take place in silico - in software. As the digital models improve, and the speed of computers continue to increase, rather than taking months to perform a phase 1 trial this may be carried out in a few days on a supercomputer. Even if not 100% accurate to start with, it should at least increase the success rate of drug development.
Click on resource name for more details.
Revolutionary bio-inspired molecules accelerate bone healing: a breakthrough for regenerative medicine
TU Dresden (University of Technology) - 28-Apr-2023
Novel molecules enhance bone regeneration in mice by 50%, paving the way for treatments for bone fractures and related conditionsRead more...
World's first 3D female anatomy model is available in the Complete Anatomy app
Healthline - 09-Feb-2022
Female model allows health professionals have a better perspective on women's healthRead more...
Technology to create virtual tumours and treat them with AI-designed nanoparticles
Nano Magazine - 22-Sep-2021
Virtual cancer tumours can be grown and we can design personalised nanoparticles to treat themRead more...
EVONANO platform makes virtual tumour growth and drug design possible
University of Bristol - 22-Sep-2021
AI-powered software can be an alternative for expensive and extensive lab workRead more...
Study on the accuracy of in-silico trials as compared to traditional trials
Medgadget - 24-Jun-2021
Virtual clinical trial can reduce the cost and time required while reducing riskRead more...