Key points from article :
Nicotinamide mononucleotide (NMN) and exercise may work together for even greater effects.
Exercise increases NAMPT, potentially allowing more NMN in the body to be converted to NAD+.
Researchers conducted the first clinical trial studying the combined effects of NMN and exercise in humans.
Subjects (men, 40; women, 8) were Chinese, young or middle-aged, healthy, and regular but amateur runners.
For six weeks, they took either a placebo or 150 mg, 300 mg, or 600 mg of powdered NMN twice per day.
Exercised 5-6 sessions per week, with 2 sessions of cycling and 3-4 of running. Each session lasted between 40-60 minutes.
No significant differences in weight loss and body composition.
A dose-dependent improvement of fitness at more moderate effort of the first ventilatory threshold, attributed to ​increased utilization of O2 by skeletal muscle.
An improvement in cardiac function is another typical cause.
Study by Guangzhou University published in JISSN.
