Key points from article :
Nicotinamide mononucleotide (NMN) and exercise may work together for even greater effects.
Exercise increases NAMPT, potentially allowing more NMN in the body to be converted to NAD+.
Researchers conducted the first clinical trial studying the combined effects of NMN and exercise in humans.
Subjects (men, 40; women, 8) were Chinese, young or middle-aged, healthy, and regular but amateur runners.
For six weeks, they took either a placebo or 150 mg, 300 mg, or 600 mg of powdered NMN twice per day.
Exercised 5-6 sessions per week, with 2 sessions of cycling and 3-4 of running. Each session lasted between 40-60 minutes.
No significant differences in weight loss and body composition.
A dose-dependent improvement of fitness at more moderate effort of the first ventilatory threshold, attributed to increased utilization of O2 by skeletal muscle.
An improvement in cardiac function is another typical cause.
Study by Guangzhou University published in JISSN.