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New type of medicine made from living bacteria


Key points from article :

Bacteria created that mops up excess ammonia in the body.

Engineered to control how they operate in the human gastrointestinal tract.

High levels can be fatal for people with liver damage and rare genetic disorders.

Microbes boosted survival rates in susceptible mice.

Small trial in healthy people found the bacteria were safe to take.

Developed by Synlogic which was co-founded by MIT.

Technique could also be used to produce something beneficial for the patient.

The study was published in Science Translational Medicine journal.

Can be used to add or remove products from the body

Mentioned in this article:

Company Representative

Senior leader in discovery and development of novel therapeutic drugs accessing the GI tract.


Head of Structural and Synthetic Biology Department of Infectious Disease at Imperial College London.


Journal which publish papers with topics related to translational medicine.


Company designing Synthetic Biotic medicines.