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New antimicrobial hydrogel heals drug-resistant wound infections

Immune peptides bound hydrogel offers new hope in fighting global antibiotic crisis

13-May-2021

Key points from article :

Researchers developed an antibacterial hydrogel that can kill antibiotic-resistant bacteria.

Conceived as a wound dressing, and is composed of antimicrobial peptides which are naturally produced by the immune system.

The gel binds the peptides together and protects them, yet allows them to still kill bacteria.

“With these peptides, there is a very low risk for bacteria to develop resistance against them, since they only affect the outermost membrane of the bacteria,” - Martin Andersson, study co-author.

The peptides are highly effective, quite delicate and rapidly degrade when they come into contact with blood.

Researchers discovered a way to protect the peptides while maintaining their efficacy.

They bound the peptides within a protective hydrogel, meaning they degrade much more slowly.

A spin off company called Amferia AB which is working on commercializing the technology.

Study by Chalmers University of Technology published in ACS Biomaterials Science & Engineering.

Mentioned in this article:

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Chalmers University of Technology

University located in Gothenburg, Sweden

Martin Andersson

Professor in Chemistry and Chemical Engineering, Applied Surface Chemistry at Chalmers University of Technology

Topics mentioned on this page:
Antibiotic Resistance