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New antibiotic zosurabalpin offers hope against deadly hospital infections

Scientists hail "exciting" discovery against superbug Crab, paving the way for future antibiotics

04-Jan-2024

Key points from article :

New antibiotic zosurabalpin worked "extremely well" in test-tubes and mice, and now shows promise against drug-resistant bacteria.

Effective against infections caused by the carbapenem-resistant Acinetobacter baumannii (Crab) bacterium.

CRAB causes severe infections in hospitals with high mortality rate.

Zosurabalpin disrupts Crab's protective membrane construction.

Completed "first-in-man" studies & were "set up now to do full clinical trials in people with the infection", -  Laura Piddock, GARDP's scientific director.

Commercialization and global access may take years due to cost, but there is definite hope for new antibiotics.

Study led by researchers from Roche, published in the journal Nature.

Mentioned in this article:

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Laura Piddock

Director of Scientific Affairs at Global Antibiotic R&D Partnership (GARDP) and Professor of Microbiology at University of Birmingham.

Nature

Scientific journal covering research from a variety of academic disciplines, mostly in science and technology

Roche

Multinational healthcare company that operates under Pharmaceuticals and Diagnostics divisions all over the world

Topics mentioned on this page:
Antibiotic Resistance
New antibiotic zosurabalpin offers hope against deadly hospital infections