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Naturally occurring particles in cow's milk could revolutionise oral drug delivery

Study may provide a safe and effective way to take powerful injectable medications by mouth

26-Apr-2024

Key points from article :

Researchers at King's College London studied whether particles found in cow's milk could be used to deliver medicine directly through the mouth.

Many powerful new drugs, including RNA therapies, must be injected because they break down in the stomach, making them inconvenient and expensive.

The scientists focused on tiny natural particles in milk called extracellular vesicles (EVs), which can protect their contents and move through the body.

They loaded these milk-derived EVs with a special RNA drug and tested it on a rat model of inflammatory bowel disease (IBD).

The RNA drug successfully traveled within the EVs, reached the target area, and reduced inflammation in the rats' intestines.

This study suggests that cow's milk particles could offer a safe, natural way to deliver oral RNA therapies for a wide range of diseases, potentially leading to cheaper and more accessible treatments.

The study was published in the Journal of Nanobiotechnology.

Mentioned in this article:

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Journal of Nanobiotechnology

Open access peer-reviewed journal

King's College London

Public research university

Topics mentioned on this page:
Drug Delivery, Nanomedicines
Naturally occurring particles in cow's milk could revolutionise oral drug delivery