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Glucosamine, a supplement to prevent overall and cause-specific deaths

Human and animal research supports longevity benefits of glucosamine and chondroitin supplements


Key points from article :

Glucosamine is one of the most commonly used supplements to promote joint health and treat other aches.

Naturally occurs in cartilaginous joint tissues and is involved in protein and lipid synthesis.

Variety of foods are rich in glucosamine; however, cooking denatures it.

It is cheap, convenient, and readily available.

Inhibits NF-kB protein complex, a central mediator of inflammation and aging, especially with chondroitin.

A clinical trial confirmed the anti-inflammatory effects and other health benefits in humans.

Reduction of cancer mortality risk by 13%, respiratory disorders by 41%, and other causes by 33%, lowering all-cause mortality by 18%.

Shown to work in a similar way to aspirin by reducing platelet aggregation.

Correlates with reduced all-cause mortality.

Glucosamine and chondroitin was associated with 65% reduction in cardiovascular mortality and 39% reduction in all-cause mortality.

May be a caloric restriction mimetic, which is known to increase lifespan in multiple species.

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