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Genes not the best predictor of human disease risk

Risks arise mostly from metabolism, environment, lifestyle, and exposure to various chemicals

18-Dec-2019

Key points from article :

DNA is not your destiny, and SNPs are duds for disease prediction.

Common diseases have a genetic contribution of 5 to 10 percent at most.

This includes cancers, diabetes, and Alzheimer's.

Notable exceptions are Crohn’s disease, celiac disease, and macular degeneration.

These have a genetic contribution of approximately 40 to 50 percent.

Metabolites, proteins, microbiome provides more accurate measure of human disease risk.

There is a need to understand our environment and safety of food, air, and water.

Research from University of Alberta, published in PLOS ONE.

Mentioned in this article:

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David Wishart

Scientist trained in physics, biochemistry, biophysics, pharmaceutical science and computational biology

PLOS ONE

This journal covers primary research from any discipline within science and medicine

University of Alberta

University of Alberta in Canada

Topics mentioned on this page:
DNA Testing