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First human clinical trial for nicotinamide riboside


Key points from article :

Nicotinamide riboside (NR) is a form of Vitamin B3.

University of Iowa researchers have shown that the compound is safe for humans.

It increases levels of NAD+ that is critical for cellular energy production and protection against stress and DNA damage.

Levels of NAD+ diminish with age.

Previous mice studies have also shown it increases lifespan.

The study was published in the Nature Communications journal.

Mentioned in this article:

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Carver College of Medicine

Medical school of the University of Iowa.

Charles Brenner

Chair and Head of Biochemistry at University of Iowa.


An integrated global nutraceutical company devoted to improving the way people age.

Nature Communications

Journal covering all topics in physics, chemistry, and biology

Queen's University Belfast (QUB)

Public Research university.

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