Key points from article :
Scientists developed the first human “Organ-on-a-Chip” model of the lung.
Organ Chip model recapitulates human organ-level physiology and pathophysiology with high fidelity.
Body-on-Chips platform quantitatively predicts human drug PK/PD behavior in vitro.
Platform is run by “Interrogator”, which can culture, perfuse, and link many living human Organ Chips.
Vascular channels of the chips are linked via a central arterio-venous (AV) fluid mixing reservoir.
Collected data is used to predict changes in drug levels over time.
