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Biogen's Alzheimer's drug trials halted

Another promising candidate not making it to the finish line

21-Mar-2019

Key points from article :

Biogen halting two phase three clinical trials of an Alzheimer's drug.

Aducanumab targeted the buildup in the brain of beta-amyloid.

Early results showed improved cognitive function and reduced amyloid in the brain.

Amyloid deposition starts a decade or so before symptoms and it's too late to treat it then.

Decision to stop the aducanumab trials was not due to any safety concerns.

Futility analysis found the trials were unlikely to meet their primary goals at completion.

Mentioned in this article:

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Biogen

Company specialized in the discovery, development, and delivery of therapies for the treatment of neurological diseases

Eisai

Pharmaceutical company focusing to cancer and neurology drugs.

Richard Isaacson

Associate Professor of Neurology at Weill Cornell

Topics mentioned on this page:
Mental Health