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Antibodies restore brain function of old mice back to their young days

Possible treatment for neurodegenerative diseases of old age

05-Apr-2019

Key points from article :

Scientists developed antibodies to block a protein and rejuvenate old brains in mice.

A new target for treatment of neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

Humans and mice have gene to produce CD22 protein - responsible for age-related cognitive losses.

CD22 protein levels in microglia cells of brain increases with age.

Possibility to develop a drug to restore mental acuity of older population in the future.

2 months of continuous treatment improved performance of mice significantly.

Outperformed control mice of same age in two different learning and memory tests.

Study by the Stanford neuroscientists published in Nature.

Mentioned in this article:

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Nature

Scientific journal covering research from a variety of academic disciplines, mostly in science and technology

Stanford University School of Medicine

Medical school that improves health through discoveries and innovation in health care, education and research

Tony Wyss-Coray

Professor at Stanford University School of Medicine

Topics mentioned on this page:
Mental Health