In this episode, Dr. Brian Kennedy, Director of the Centre for Healthy Longevity at the National University of Singapore and former CEO of the Buck Institute, dives deep into the future of ageing science. He explores the role of diagnostics, supplements, and emerging interventions — from AI and stem cells to psychedelics — and shares practical, scalable insights to extend healthspan and improve quality of life.

Key Points:

Brian Kennedy envisions a future where AI, personalized diagnostics, and validated supplements extend healthspan. He urges shifting from reactive sick care to proactive ageing strategies accessible to all, not just the elite.

• From Sick Care to Preventative Health: Kennedy emphasizes a shift from reactive “sick care” to proactive healthcare, focusing on keeping people healthy through lifestyle, early diagnostics, and continuous monitoring rather than only treating diseases after they emerge.
• Measure First, Then Intervene: He stresses the importance of measuring biomarkers, nutrient levels, and biological age before taking supplements or interventions. Personalized, data-driven approaches can prevent unnecessary or harmful treatments and optimize long-term health.
• The Promise and Pitfalls of Longevity Supplements: Kennedy supports safe experimentation with supplements like AKG, sublingual NAD, and Rejuvant — which he personally uses — but cautions against combining too many unvalidated compounds without monitoring outcomes.
• AI, Gene Therapy, and Stem Cells: He sees enormous promise in AI-driven diagnostics and predictive ageing clocks, along with future potential in safe gene therapy and stem cell interventions to slow or even reverse aspects of ageing.
• The Longevity Movement and PR Problem: While the field is growing rapidly, Kennedy notes that longevity still suffers from a “billionaire-only” perception and misinformation. He advocates for scalable, accessible tools that democratize healthy ageing for all.
• Singapore as a Blueprint for Healthy Ageing: Singapore’s forward-thinking policies, trusted governance, and small population make it an ideal testbed for healthy longevity initiatives that could become global models in the near future.