Epigenome editing - technology safer and reversible than CRISPR
Science - 01-Jun-2022Leaves DNA sequence unaltered while retaining the ability to specifically home
Join the club for FREE to access the whole archive and other member benefits.
Epi-therapeutic medicines working on epigenome editors
The vast majority of human disease is governed by the epigenome, the subtle machinery that controls the volume of gene expression in cells. Tune Therapeutics is pioneering the creation of epi-therapeutic medicines with its powerful and precise epigenomic control platform, TEMPO. Unlike genome editing, TEMPO dials the volume of gene expression up or down towards healthy levels, without breaking or permanently rewriting DNA – and it can do this in multiple genes at once. This genetic tuning approach allows to change cell fate and function at will, unlocking the ability to reverse pathways of cancer, genetic disease and aging. Their approach effectively expands the potential reach of genetic medicine – from targeting a limited range of rare conditions, to overcoming thousands of complex and chronic diseases that currently have no curative treatment.
Visit website: https://tunetx.com/
Details last updated 01-Jul-2022
Leaves DNA sequence unaltered while retaining the ability to specifically home