Assistant Professor Tsai received her Ph.D. in Dr. Gustavo Leone's lab at the Ohio State University (2009), where she studied the mechanisms by which mammalian E2F transcription factors control cell proliferation. She showed the functional redundancy among E2F activators during development and the specific roles of E2F family members during long-term maintenance. After her Ph.D., she did her postdoctoral training in Dr. Brian Kennedy's lab at the University of Washington and continued her research at the Buck Institute. She investigated the role of mTORC1 downstream translation effecter, 4E-BP1, in regulating metabolic homeostasis during the progression of type II diabetes and aging. Since February 2017, she started her lab as an Assistant Professor at the Department of Physiology at the National University of Singapore. Her study focuses on exploring how protein homeostasis in the regulation of muscle health. Using transgenic mouse models and primary 3D in vitro models of skeletal muscle, her lab studies the aging process at molecular levels to provide an explicit picture of muscle aging for potential therapeutic usage.