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Samantha Spellicy

Neuroscience PhD student at the University of Georgia Graduate School

I work in the Regenerative Bioscience Center at the University of Georgia as a PhD Student in the laboratory of Dr. Steven Stice, Ph.D.


In the lab I study the therapeutic potential of Neural Stem Cell-Derived Extracellular Vesicles (NSCEV) in ischemic stroke. For this work Implement standard sterile culture techniques to maintain various cell populations including neural stem cells, mesenchymal stem cells, neurons, microglia, motor neurons, and murine primary cultures utilized for experimentation. From these cultures I collect and isolate neural stem cell-derived extracellular vesicles (NSCEVs) to assess their therapeutic potential and neuroprotective efficacy in animal models of stroke, such as porcine, murine, and aged murine. Through these studies have eployed tenents of gait and behavior testing, as well as analysis of biological specimens such as blood and tissue.

In development of my own projects, I spearheaded novel live cell imaging experiments here at UGA through Spatial Light Interference Microscopy (SLIM) to visualize labeled and unlabeled extracellular vesicle uptake and corresponding changes in dry mass in recipientcells

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See also: Academia University of Georgia - The University of Georgia, a land-grant and sea-grant university

Details last updated 21-Jan-2020