Associate professor and Principal Investigator, working on healthy metabolism particularly in the context of aging, rare diseases, and cardiovascular health. Support by ERC Starting Grant and ZonMw/Veni grant.

The general theme of our research is metabolism, and several research lines are geared towards understanding the development of metabolic diseases. These can be subdivided in common, often age-related, diseases and inborn errors of metabolism.

We are studying how genes, nutritional components, and pharmacological compounds affect the aging process. In addition, we aim to integrate these factors to understand how certain genetic traits render an organism susceptible to the harmful effects of diets. Most of this work is performed with the worm C. elegans, but we also use other in vitro and in vivo models.