Dr. Ralph DeFronzo graduated from Yale University with a degree in biology and biochemistry before going on to Harvard Medical School.  Following internal medicine training at Johns Hopkins, he completed fellowships in Endocrinology (NIH, Baltimore City Hospital) and Nephrology (Hospital of the University of Pennsylvania). He holds the Joe R. & Teresa Lozano Long Distinguished Chair in Diabetes in the Long School of Medicine at UT Health San Antonio, where he has been on the faculty since 1988. Dr. DeFronzo is directly responsible for many seminal advances achieved in diabetes over the last 50 years. He was a leader in developing the concept of insulin resistance, the defining characteristic of Type 2 diabetes, resulting in novel ideas about the development and progression of diabetes.