Research in the Kishore laboratory is focused on several specific areas within the overall theme of identifying novel insights into cardiovascular disease mechanisms and the translational integration of mechanistic studies in relevant physiological models. The major focus of ongoing research encompasses multiple aspects of stem cell based therapies for post-infarct myocardial and other ischemic tissue repair and regeneration. The laboratory is currently investing significant efforts on developing novel strategies to enhance the therapeutic benefits of stem cell therapy (of both adult and embryonic/ iPS cells) specifically their survival, function, and differentiation both in vitro and in physiologically relevant in vivo models of myocardial injury.