ARCUS gene editing technology effectively eliminates mutant mitochondrial DNA
Biospace - 04-Dec-2023Potential therapeutic approach for mitochondrial and other genetic diseases
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Genome editing technology to develop a novel medicines
Precision BioSciences, Inc. (Nasdaq: DTIL) is a clinical stage gene editing company developing in vivo gene editing and ex vivo allogeneic CAR T therapies with its highly precise and versatile ARCUS genome editing platform. ARCUS uses sequence-specific DNA-cutting enzymes, or nucleases designed for gene knock out, as well as highly complex edits for gene insertion and/or gene repair. Precision’s allogeneic CAR T pipeline consists of multiple investigational candidates in early-stage clinical trials, including its lead CD19 targeting candidate, azercabtagene zapreleucel (azer-cel; PBCAR0191) for post-auto CAR T patients with non-Hodgkin lymphoma.
Visit website: https://precisionbiosciences.com/
Details last updated 05-Dec-2023
Potential therapeutic approach for mitochondrial and other genetic diseases