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Nutrition and the biology of ageing

Event about nutrition and its impact on metabolism organized by British Society for Research on Ageing

12-Sep-2022 to 14-Sep-2022

Ageing is associated with ill-health, diseases and disability. There is an ongoing demographic shift with populations ageing globally, and an urgent need for strategies to improve age-related health. Recent research into the mechanisms of ageing show that despite its complexity, ageing in a range of animal models is driven by common underlying biological processes, driving multiple age-related pathologies. The discovery that ageing can be ameliorated by dietary, genetic, and pharmacological interventions opens up the prospect of preventive medicine to promote healthy ageing and delay age-related functional decline.

A major discovery is that nutrition controls ageing. Dietary restriction is the most effective way to improve age-related health across species. The key signalling pathways affecting ageing involve nutrient sensing. Diet is a well-established determinant for long-life health.

Research shows the importance of timing of feeding, specific nutrients, the nature of the effector mechanisms, the longer-term (including trans-generational) consequences of diet, and key roles played by the gut microbiota. These new findings open the way to dietary and pharmacological interventions to recapture the benefits of dietary restriction, which are difficult to maintain voluntarily.

This conference will bring together researchers working on basic molecular and cellular processes of nutrition, its impact in metabolism, with researchers identifying interventions to improve age-related health. We will provide an interdisciplinary forum for discussion on how to translate fundamental scientific findings to clinical strategies that target age-related ill-health. The broad appeal of the conference will attract delegates from a range of disciplines including biochemistry, biology and medicine across the UK and beyond working within this rapidly expanding field of research.

Invited speakers include:

• Professor Brian Kennedy, Director of Centre for Healthy Ageing, National University of Singapore

• Professor Irene Miguel-Aliaga, Imperial College, UK

• Professor Keith Blackwell, Joslin Diabetes Centre, Harvard Medical School, USA

• Professor Jane Murphy, Bournemouth University, UK

• Dr Martin Denzel, Principal Investigator at Altos Labs, Cambridge UK

• Dr Celine Halioua, Loyal for Dogs, San Francisco, USA

• Dr Joris Deelen, Principal Investigator, Max Planck Institute for Biology of Ageing, Cologne, Germany

• Dr Claire Steves, King's College London, UK

• Dr Tina Woods, Founder & CEO, Collider Health, UK

• Professor Paul Shiels, University of Glasgow, UK

• Dr Cassandra Coburn, Editor in Chief, The Lancet Healthy Longevity and author of 'Enough: How your food choices will save the planet', UK

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See also: Institute British Society for Research on Ageing (BSRA) - Scientific society which promotes and funds research into the biology of ageing

Details last updated 30-Jul-2022

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Mentioned in this Resource

Brian Kennedy

Prof of Biochemistry and Physiology at NUS, CSO Ponce De Leon Health

Cassandra Coburn

Editor In Chief at The Lancet Healthy Longevity.

Celine Halioua

CEO and founder of Loyal, interested in the biology of aging

Claire Steves

Practicing Geriatrician and Senior Clinical Lecturer at King's College London

Irene Miguel-Aliaga

Professor in Faculty of Medicine, Institute of Clinical Sciences at the Imperial College London

Jane Murphy

Professor and Deputy Dean for Research at Bournemouth University

Joris Deelen

Geneticist and Research Group leader at the Max Planck Institute for Biology of Ageing

Keith Blackwell

Senior Investigator and Section Head of Islet Cell and Regenerative Biology in Immunobiology at the Joslin Diabetes Center

Martin Denzel

Principal Investigator at AltosLabs and researcher at Max Planck Institute for Biology of Ageing

Paul Shiels

Professor of Epigenetics at University of Glasgow

Tina Woods

CEO and Co-Founder, Longevity International. Author of Live Longer with AI