When bodies lose their blueprint: A new theory of aging
Live Forever Club - 04-Nov-2025Aging emerges when cells lose shared goals—but restoring those signals can trigger rejuvenation
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Director of the Center for Regenerative and Developmental Biology at Tufts University
The capacity to generate a complex organism from the single cell of a fertilized egg is one of the most amazing qualities of multicellular animals. The processes involved in laying out a basic body plan and defining the structures that will ultimately be formed depend upon a constant flow of information between cells and tissues. The Levin laboratory studies the molecular mechanisms cells use to communicate with one another in the 4-dimensional dynamical system known as the developing embryo. Through experimental approaches and mathematical modeling, we examine the processes governing large-scale pattern formation and biological information storage during animal embryogenesis. Our investigations are directed toward understanding the mechanisms of signaling between cells and tissues that allows a biological system to reliably generate and maintain a complex morphology. We study these processes in the context of embryonic development and regeneration, with a particular focus on the biophysics of cell behavior.
Visit website: http://ase.tufts.edu/biology/labs/levin/
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