Mark is an internationally renowned scientist who has published over 200 papers including key publications in the highest impact journals (New Engl J Medicine, Lancet, Nature Medicine, Lancet Oncology, Cancer Discovery, Nature Comms, Gut). His work has been recognised by numerous national/international awards including the Vander Molen Prize for Leukaemia Research, Ely Lilly Prize, St Lukes Medal for Cancer Research, Graves Medal for Medical Research and the prestigious 2018 European Health Award.

Mark is Associate Director of Health Data Research Wales-Northern Ireland and  is Scientific Director of DATA-CAN, the UK Health Data Research Hub for Cancer. In the wake of the Cambridge Analytica/Facebook scandal, Mark led a pan European group in developing a roadmap to restore public trust in health data, published in Lancet Oncology. In the context of the recent COVID-19 pandemic, Mark and colleagues in DATA-CAN are employing a data-driven approach to understand and mitigate the effects of COVID-19 on cancer patients and cancer systems, work that recently was featured prominently in national and international media.