Jeffery is an academic researcher, serial entrepreneur, technologist, and investor who specializes in advancing the highest forms of human wellbeing. For over a decade he has conducted the largest international study on Fundamental Wellbeing, which includes the types of consciousness commonly known as: enlightenment, nonduality, the peace that passeth understanding, unitive experience, and hundreds of other terms. This resulted in the first reliable, cross-cultural and pan-tradition classification system for these types of experience. More recently, he has used this research to make systems available to help people obtain profound psychological benefits in a rapid, secular, reliable, and safe way.

Jeffery is also the founder of the Transformative Technology space, which has grown to become a multi-billion dollar ecosystem that promotes the use of science and technology to substantially raise human mental and emotional wellbeing. He conceived of the space, co-founded the first academic TransTech lab, its first conference, taught the first university-level course, organized the earliest investor meetings, and many other firsts. He serves as a formal and informal advisor to a wide range of companies and other organizations in the space, is an active early-stage investor, and is a frequent public speaker on TransTech related topics.