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Fractyl

A company aiming to bring curative therapies for patients with metabolic disease

At Fractyl, we are applying new scientific insights in intestinal biology to advance treatments and potential cures for metabolic diseases.


Our growing product pipeline leverages our minimally invasive procedural therapy, Revita™ DMR (duodenal mucosal resurfacing), which is designed to rejuvenate the lining of the duodenum and improve patient health. We are currently advancing global clinical development of Revita DMR, initially targeting patients with conditions resulting from insulin resistance, including type 2 diabetes (T2D), nonalcoholic steatohepatitis (NASH), and polycystic ovarian syndrome (PCOS), while also exploring use of Revita DMR in combination with cell and gene therapy.


We believe our breakthrough insights offer the potential to restore health to millions of patients worldwide and reduce the global economic burden of metabolic disease. We are steadfast in our commitment to creating solutions for all of our partners seeking new treatment options, efficient and cost-effective care, and better outcomes.


Fractyl is a privately held company headquartered in Lexington, Massachusetts.

Visit website: https://www.fractyl.com/

 fractyllabs

 fractyl-laboratories-inc-

Details last updated 10-Apr-2020

Fractyl Creations

Revita DMR

A minimally invasive therapeutic procedure for poorly controlled type 2 diabetes

Fractyl News

Fractyl raised $110 million to develop treatments for obesity and diabetes

Longevity Technology - 05-Feb-2024

They picked RJVA-001, a gene therapy, as their first clinical candidate

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New minimally invasive therapy for poorly controlled type 2 diabetes

News Medical - 30-Mar-2020

Pills that target the duodenal mucosa will come soon enough

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