Ever since his now 19-year-old son David developed type 1 diabetes at 11 months of age, Ed D. has been committed to creating and integrating closed-loop blood-glucose control technologies with a vision of building a bionic pancreas by the time his son headed off to college. Between 2005 and 2008, he and his PhD student, Firas El-Khatib, began conducting experiments in diabetic pigs in his laboratory at Boston University testing an early laptop-version of their bionic pancreas system. They then progressed with their clinical collaborators at the Massachusetts General Hospital to conduct over four years in-patient trials in adults and adolescents with T1D. Over the past five years, his team at Boston University, along with his clinical collaborators, have conducted over a dozen outpatient and home-use clinical trials in adults and children with type 1 diabetes testing a mobile version of their bionic pancreas, which ran on an iPhone.