Dr. Kiel's research focuses on the epidemiology of osteoporosis and related fractures, including lifestyle factors, biomarkers, and genetic factors.  He is also interested in sarcopenia and its consequences, including falls and disability.  He also has conducted multiple clinical trials targeting the musculoskeletal system.  He leads the Framingham Osteoporosis Study, and serves in leadership roles for many organizations including the NIH, American Society for Bone and Mineral Research, National Osteoporosis Foundation, and the Joint Commission. Dr. Kiel also heads the Geriomics program as a part of the Musculoskeletal Research Center.  The Program includes faculty and post-doctoral fellows appointed through Harvard Medical School who study the "omics" of age-related disease, primarily diseases of the musculoskeletal system, as well as the aging process itself.