Cellesce was founded in 2013 and is built on biochemical and bioprocess engineering expertise from the University of Bath and cell and organoid biology expertise from Cardiff University. In December 2017 Cellesce moved into the Medicentre in Cardiff, Wales.

Cellesce has invented and patented a unique bioprocess for the expansion of human-derived, normal and cancer organoids for a multitude of applications including drug discovery and organ-on-a-chip applications.

Until recently, organoids could only be grown and expanded manually. This is a technically challenging, time-consuming, and labour-intensive process resulting in small numbers of inconsistently sized organoids, limiting their suitability for use in high throughput applications and widespread use by big pharma and biotech.