Amir Lerman is an endowed named Barbara Lips Professor of Medicine and a Consultant in the Department of Cardiovascular Medicine at the Mayo Clinic Graduate School of Medicine. Lerman serves as an Associate Chair of the Department of Cardiovascular Medicine and the Director of the Cardiovascular Research Center at Mayo Clinic, and the Medical Director of the Chest Pain and Coronary Physiology Clinic. Lerman serves as the Medical Director of Mayo-Israeli startup company initiative and on the faculty of the Merage Institute for Medical Innovation.

Lerman's research goal is to increase the understanding of how the heart functions, with the long-term aim of translating this knowledge into new strategies to prevent and treat heart disease. His interests include coronary physiology and imaging, regenerative medicine, innovative technologies, and digital health.

Lerman graduated from the Technion School of Medicine in Haifa, Israel and completed his training in Internal Medicine, Cardiovascular Medicine and Invasive Cardiology at Mayo Clinic.