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Scientists create a lab-made microbe with fully redesigned DNA for the first time

Organisms can survive even with a simple genetic code

15-May-2019

Key points from article :

Scientists created world’s first living organism with a fully synthetic and radically altered DNA code.

Proves life can exist with a restricted genetic code.

Read and redesigned the genome of Escherichia coli, replacing 3 codons throughout the genome.

Chemically synthesized genetic code was introduced piece by piece to E-coli, creating the lab-made microbe Syn61.

Survives on a smaller set of genetic instructions, but growth is slow.

Future impact in mass production of drugs and useful material or production of bacteria resistant to viruses.

Research by Cambridge University, published in Nature.

Mentioned in this article:

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Jason Chin

Programme Leader at the Medical Research Council Laboratory of Molecular Biology at Cambridge University.

Nature

Scientific journal covering research from a variety of academic disciplines, mostly in science and technology

Tom Ellis

Professor of Synthetic Genome Engineering at Imperial College London.

University of Cambridge

Collegiate research university in Cambridge, United Kingdom

Topics mentioned on this page:
Synthetic Biology