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NMN improved muscle glucose uptake in prediabetic women

22-Apr-2021

Key points from article :

A small clinical trial shows that NMN improved the ability of insulin to increase glucose uptake in skeletal muscle.

Studied 25 postmenopausal women who had prediabetes.

NMN also improved expression of genes involved in muscle structure and remodeling.

"It is premature to make any clinical recommendations based on the results from our study," - Samuel Klein, Senior investigator.

Supplementing animals with NMN slows and ameliorates age-related decline in the function of many tissues.

Beneficial effects in rodents led several companies to market the compound as a dietary supplement or a neutraceutical.

Many people now take NMN despite the lack of evidence to show clinical benefits in people.

More studies to determine whether NMN has beneficial effects in the prevention or management of prediabetes or diabetes.

Continuing to evaluate NMN in another trial involving men as well as women.

Study by Washington University School of Medicine published in Science.

Further studies to confirm clinical benefits of this anti-aging compound in a large sample

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Academic

William H. Danforth Professor of Medicine at Washington University School of Medicine

Journal

Peer-reviewed academic online journal of the American Association for the Advancement of Science (AAAS)