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Hybrid micro-robot to advance precision drug delivery and single-cell analysis

Electric- and magnetic-powered tiny robot able to identify, capture, and transport single cell autonomously

28-Mar-2023

Key points from article :

Researchers developed a hybrid micro-robot (~10 microns) that can be controlled and navigated using electric and magnetic fields.

It can transfect a drug and/or gene into the captured targeted single cell.

"Developing the micro-robot's ability to move autonomously was inspired by biological micro-swimmers, such as bacteria and sperm cells," - Gilad Yossifon, corresponding author.

Identifies the type of cell and its condition using a built-in sensing mechanism based on the cell's unique electrical properties.

As a demonstration, it captured single blood/cancer cells, a bacterium, and distinguished cells that are healthy, damaged, or dead.

After identifying the desired cell, the micro-robot captured it and moved the cell to where it could be further analyzed.

Helps in single-cell analysis, medical diagnosis, drug transport and screening, surgery, and environmental protection.

"Among other things, the technology will create a 'laboratory on a particle."

Research by Tel Aviv University published in the journal Advanced Science.

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Advanced Science

Journal publishing research in materials science, physics and chemistry, medical and life sciences and engineering

Gilad Yossifon

Professor at Tel Aviv University and Head of the TAU Micro-Fluidics and Nano-Robotics Laboratory

Tel Aviv University

Public Research university.

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Nanobots
Hybrid micro-robot to advance precision drug delivery and single-cell analysis