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Caltech researchers have developed a wearable sweat sensor that uses special nanoparticles to monitor the human body in real time, paving the way for personalized healthcare. The team, from the Andrew and Peggy Cherng Department of Medical Engineering, created "printable molecule selective nanoparticles" that can detect specific molecules, like drugs or vitamins, by imprinting their shape and measuring electrical signals in sweat.
The team used a nickel hexacyanoferrate core in the nanoparticles, which is stable in biological fluids, allowing long-term tracking of biomarkers. In their study, published in Nature Materials , they demonstrated the sensors' ability to monitor cancer drug levels in patients remotely, offering potential for dose personalization.
The sensors can also track other health indicators, such as vitamin C, amino acids, and kidney function markers, all integrated into a single wearable patch. This innovation could revolutionize chronic disease management by enabling continuous, noninvasive monitoring tailored to individual needs.
