Join the club for FREE to access the whole archive and other member benefits.

Blood pressure fluctuations predict risk of heart attack and stroke

Study calls for effective monitoring and amlodipine-based treatment plan

31-Jan-2024

Key points from article :

Blood pressure fluctuations over time could be used to identify patients at greatest risk of heart attack and stroke.

Study analyzed over 8,000 patients with high blood pressure for 20+ years.

Those with high variability had a 16% high risk of cardiovascular events.

Over half of the events occurred in patients with well-controlled blood pressure under current guidelines.

Systolic pressure variability of 13mmHg or more over 5 years suggests significantly increased risk.

Amlodipine, a calcium channel blocker, may help reduce BP variability and risk.

More research needed to determine optimal method for measuring variability.

“..studying the possibilities of incorporating data from home monitoring into clinical decision-making," - Peter Sever, study co-author.

Research by ICL, published in the European Heart Journal.

Mentioned in this article:

Click on resource name for more details.

European Heart Journal

Scientific Journal providing information about cardiovascular diesases

Imperial College London (ICL)

Public research university with an international reputation for excellence in teaching and research

Peter Sever

Professor of Clinical Pharmacology & Therapeutics and Honorary Consultant Physician at the Imperial

Topics mentioned on this page:
Blood Pressure, Heart Disease
Blood pressure fluctuations predict risk of heart attack and stroke