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Alzheimer's-like disease discovery could mean new targets for treatments

Late linked to the accumulation TDP-43 protein rather than amyloid and tau

30-Apr-2019

Key points from article :

Millions of people have been misdiagnosed with Alzheimer's disease.

"Late" (limbic-predominant age-related TDP-43 encephalopathy) is a distinct disease.

It tends to cause a more gradual decline in memory.

It may partly explain why finding a dementia cure has failed so far.

Though these dementias can co-exist.

Late appears to affect the most elderly, i.e. people over 80.

Having a better understanding of Late might lead to the discovery of new treatments.

Mentioned in this article:

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Pete Nelson

Professor of Pathology in Division of Neuropathology and Sanders-Brown Center on Aging.

University of Kentucky

Public Research university.

Topics mentioned on this page:
Alzheimer's Disease