His research intersests include:

• Investigating modifiable lifestyle factors such as physical exercise, cognitively stimulating activities and daily total caloric intake; and their impact on aging and mild cognitive impairment (MCI).
• Examining the relationship between emotional behavior, aging and MCI; with particularl interest in developing an early prediction model of dementia by utilizing neuropsychiatric and modifiable life style parameters in MCI.

He is also a coinvestigator of the Mayo Clinic Study of Aging, funded by the National Institutes of Health (NIH).

He also has done research on the neuropsychiatric aspect of Primary Progressive Aphasia and Corticobasal Degeneration.