I am a neurologist who obtained his M.D. degree at the University of Ancona in Italy. After completing my residency in Neurology, I pursued a Ph.D. in Neuroscience, which prompted me to join the Center for Sleep and Consciousness at the University of Wisconsin-Madison. There, I developed a cohesive research program to study the complex reciprocal interaction between the sleep/wake cycle and glial cells. In 2019 I joined the University of Bristol, where I am currently investigating the cellular consequences of sleep disruption and enhancement in health and disease.

Our broad scientific goal is to understand the mechanisms and functions of sleep. Our current research is focused on assessing the consequences of sleep disruption and enhancement in health and disease. These investigations are performed using a combination of morphological and functional methods in both animals and humans.

Sleep disruption is developing into a major problem in modern societies and the health consequences of insufficient sleep are numerous and impactful. Our organism responds to sleep disruption with rapid and extensive changes at molecular, biochemical, and functional levels. These modifications are adaptative at first, but, over time, they may become maladaptive, leading to lasting and serious consequences. Our research aims to understand the short- and long-term effects of sleep disruption at cellular and system levels.