Ageing affects heart health by causing mitochondrial dysfunction

Live Forever Club - 28-Oct-2024

Chronic inflammation and fibrosis further damage the heart health

Nanotechnology revives cellular energy: A breakthrough in mitochondrial regeneration

Nanowerk - 20-Sep-2024

New research from Texas A&M develops nanoflowers to restore cellular energy

Orsobio secures $67m to revolutionize metabolic disease treatment

Longevity Technology - 09-Sep-2024

Boosting fat loss and preserving muscle with cutting-edge mitochondrial therapy

Vandria secures $30.7m to advance groundbreaking mitochondrial therapy for neurodegenerative diseases

Hevolution Foundation - 21-Aug-2024

New funding propels innovative mitophagy-inducing lead compound into clinical trials targeting Alzheimer’s and Parkinson’s

Lucy Therapeutics raises $12.5M to develop mitochondrial therapies

Longevity Technology - 31-May-2024

Company is developing therapies for Alzheimer's, Parkinson's, and Rett syndrome

Timeline's Mitopure demonstrates potential to reverse immune system ageing

Business Wire - 06-May-2024

Research underscores potential to revolutionise approach to healthy ageing

Silicon Valley startup aims to extend human lifespan with mitochondrial transplants

Live Forever Club - 12-Apr-2024

Research aims to extend lifespan and unlock new levels of human health

Cell malfunctions can cause information leakage and trigger inflammation

University of Virginia School of Medicine - 05-Mar-2024

The discovery may improve inflammation treatment and anti-ageing interventions

Red light exposure may lower blood sugar levels after meals

Independent - 21-Feb-2024

It reduced blood sugar spikes and overall levels in healthy individuals

Daily choices like exercise, diet, and even how you breathe affect your mitochondria

Live Forever Club - 09-Feb-2024

Making small changes to your lifestyle can have a significant impact on health

A cellular protein called HKDC1 tidies up mitochondria and lysosomes

Interesting Engineering - 01-Jan-2024

This discovery paves the way for potential anti-ageing therapies

$20.6 million fuels Vandria's mission to conquer ageing and chronic diseases

Longevity Technology - 14-Dec-2023

Mitophagy-boosting drug candidate VNA-318 preps for clinical trials

MitoRx's $5M funding sets the stage for treating muscle and lung diseases

Longevity Technology - 14-Dec-2023

Company's drug targets the root cause of diseases like Duchenne and COPD

ARCUS gene editing technology effectively eliminates mutant mitochondrial DNA

Biospace - 04-Dec-2023

Potential therapeutic approach for mitochondrial and other genetic diseases

New peptide-based technology selectively erases ageing cells

Ulsan National Institute of Science and Technology (UNIST) - 14-Sep-2023

Mitochondria targeting could lead to new treatments for age-related diseases

New blood test may help in early detection of Parkinson’s disease

Independent - 30-Aug-2023

The test could identify drugs that reverse or slow down DNA damage and disease

Mitochondria-targeted compound prevents and treats metabolic syndrome in mice

Buck Institute - 07-Jul-2023

Selectively inhibits problematic free radicals - potential breakthrough in treatment of chronic diseases & ageing

Summary of Chris Rinsch presentation at Longevity Med Summit

Live Forever Club - 16-May-2023

Explained the production and mechanisms of Urolithin A, and trial results of Timeline's Mitopure

cellvie closes $5.5 million of financing to develop its allogeneic mitochondria therapies

KIZOO Technology Ventures - 06-Feb-2023

Mitochondria dysfunction is linked to several ageing-related diseases, including neurodegeneration, so a big potential market

Mutated mtDNA acts as a molecular target for therapeutic treatments of age related diseases

University of Cologne - 16-Dec-2022

Targeting and eliminating mutated mtDNA by subjecting it to autophagy with rapamycin been successful

Mitochondria boosting therapy rejuvenates immune system of mice

Longevity Technology - 11-Oct-2022

If successful in humans it would improve the outcome of many age-related diseases

Longevity Technology interviews cellvie CEO, Alex Schueller, about therapeutic mitochondria

Longevity Technology - 14-Sep-2022

Initially targeting ischemia-reperfusion injury, TMT has potential to treat multiple age-related diseases

$72m funding launching Pretzel Therapeutics pioneering mitochondrial therapies

Biospace - 12-Sep-2022

Pretzel targets genome correction, genome expression modulation and mitochondrial quality control

MitoRx Therapeutics' CEO shares insights on fundraising and pitching to investors

UK Innovation & Science Seed Fund - 20-Jul-2022

Effectively communicating to investors will translate an ideology into a social benefit

Restructured mitochondrial metabolism linked to survival of human eggs

STAT - 20-Jul-2022

Complex I production temporarily halted in quiescent oocytes, promoting fertility

Mitochondrial transplants show efficacy in achieving longevity in humans

Lifespan.io (LEAF) - 19-Jul-2022

Mitochondrial transplant raise energetics of the body, so it can withstand longevity treatments

Urolithin A can increase mitochondrial health in living joint tissue and improved mobility

Business Wire - 07-Jul-2022

Mitopure can improve mitochondrial health and counteract age-related muscle function decline

Buck researchers discover mitochondrial protein that can increase lifespan

Buck Institute - 18-May-2022

In yeast, increasing Tom70 delays ageing related mitochondrial dysfunction

Amazentis’ proprietary Urolithin A-clinically proven to improve muscle function

EurekAlert! - 17-May-2022

Mitopure will be offered inside Nestlé Health Science products

New longevity startup MitoRx Therapeutics is developing mitochondria protective drugs

Longevity Technology - 25-Apr-2022

Targeting age-related diseases, the company's pre-clinical compounds to progress to the clinic

Senior UCLA scientists public states aim to fight aging to impact numerous diseases

University of California, Los Angeles (UCLA) - 24-Mar-2022

Great to see the concept of reversing aging becoming a mainstream ambition - it hasn't always been that way!

New study unveils the role of tau in neurodegenerative disease

Buck Institute - 20-Jan-2022

Interactions with mitochondrial & synaptic proteins highlight targets against Tau-mediated disease

Improving mitochondrial function enhances colour vision in old age

New Atlas - 24-Nov-2021

Long wavelength exposure partially restores ATP and improves eye function

Three minute exposure to deep red light can improve your eyesight

University College London (UCL) - 24-Nov-2021

Morning exposure to long wave deep red light showed 17%-20% improvement in colour vision

Mitlets improve immunity and treat many age-related diseases

Longevity Technology - 22-Oct-2021

Experimental therapy to transfuse healthy mitochondria from multiple donors

A new nanoreactor repaired the damaged region in cells by supplying ATP

Singularity Hub - 21-Sep-2021

Energy generation in living cells by programmed exosome fusion

Complicated connection between protein shape and mitochondrial health, causing aging

Buck Institute - 07-Sep-2021

The “bad” process of pore opening and the “good” process of UPRmt - connection revealed

Penetrable sunscreen agents could reverse skin damage and ageing

SciTechDaily - 12-Aug-2021

Two novel compounds fuel mitochondria to maintain energy balance and lower UV damage in the skin

Liver-fat content and bodyweight reduction with effective use of CB4211

GlobeNewswire - 10-Aug-2021

Mitochondrial genome used to potentially treat fatty liver and prevent obesity

Elamipretide: a drug to protect your eyes from AMD

Ophthalmology Times - 07-Jul-2021

Elamipritide protects your retinal cells from undergoing degeneration

Injecting new mitochondria to replace old, damaged mitochondrial DNA in humans

Lifespan.io (LEAF) - 02-Jun-2021

Potential treatment for mitochondrial diseases & dysfunction, and extends lifespan

Recharge your mitochondrial batteries to live longer

Longevity Technology - 27-May-2021

Breakthrough in longevity research - cellular energetics may stop or even reverse the ageing process

NR supplementation restored youthfulness to blood in older mice

Lifespan.io (LEAF) - 18-May-2021

Lowers age-related defects of blood stem cells & make stem cell transplants more effective

Folds in mitochondria membrane are lost as we age - reducing production of ATP

I Spy Physiology - 12-May-2021

Antioxidant treatment reversed mitochondrial ageing via cardiolipin in mice

A natural compound reverses skin wrinkles and hair loss in mice

Longevity Technology - 08-Apr-2021

Targets mitochondrial dysfunction - cosmeceuticals on its way to reverse ageing signs in humans

You can have too much of a good thing - including exercise

The Scientist - 23-Mar-2021

2.5 hours of HIIT in a week reduces mitochondrial respiration, meaning less energy for the body

Highest exercise load lead to reduction in intrinsic mitochondrial function

The Scientist - 23-Mar-2021

Substantial mitochondrial respiratory impairment is included with excessive exercise

CohBar's lead candidate may initiate clinical trials in 2022

Longevity Technology - 16-Mar-2021

Mitochondrial-based therapy enters IND to tackle IPF and other fibrotic diseases

NAD+ reduces age-related amyloidosis and mitochondrial dysfunction

Lifespan.io (LEAF) - 05-Feb-2021

Boosting NAD+ levels improves health span and can treat age-related diseases

Mitrix gains funding to transfuse young mitochondria

Longevity Technology - 28-Jan-2021

Trials on mitochondrial transfusion might help tackle many ageing diseases

Inhibition of mitochondrial DNA might suppress tumour growth

Nature - 04-Jan-2021

IMTs degraded 1 in 3 cancer cell lines in vitro, and early promise in mice

Antihypertesive drug found a new purpose in ageing

EurekAlert! - 18-Dec-2020

Big gains in c. elegans life expectancy rarely translates to humans, but another avenue to research

Red light therapy could be the clue to restore your eyesight

China Global Television Network (CGTN) - 13-Dec-2020

Red light improved health and lifespan of fruit flies; might work on humans too

Decoded - why travelling through space can make you older

iNews - 25-Nov-2020

Mitochondrial damage accelerates ageing on exposure to space radiation and microgravity

Regulatory role of GDF 15 related to ageing and metabolism in humans and mice

Longevity Technology - 06-Aug-2020

Discovery of this homeostatic function just may be the first step but it looks promising

Scientists go where no gene-editing tool has gone before

Lifespan.io (LEAF) - 14-Jul-2020

DddA able to target mitochondrial DNA (mtDNA) by splitting in half and hitching a ride

A gene editing tool to treat mitochondrial mutations

The Scientist - 09-Jul-2020

Derived from bacterial toxin - can make single base pair changes

Humanin is a regulator peptide of healthspan and lifespan

Science Daily - 24-Jun-2020

Longer life results in less offspring - sounds like the ideal compromise to me!

Increasing ovarian NAD+ improved mitochondrial function in mice egg cells

Lifespan.io (LEAF) - 11-Jun-2020

Supplementation also shown to reverse ovarian ageing

Drug that can safely reverse obesity and insulin resistance developed

Medical Xpress - 08-Jun-2020

Proven in mice study to be non-toxic, nor affects brain hunger cues

Experts develop new novel detection method for mitophagy

Lifespan.io (LEAF) - 28-May-2020

A discovery proven to be of help in therapeutic studies of neurodegeneration

Possible culprits in genetic diseases, cancer, and ageing found

National Institute on Aging - 14-May-2020

Research shows it could be caused by mitochondrial DNA mutations

Vitamin B3 is a good option to correct the NAD+ deficit in humans

Phys.org - 14-May-2020

NAD+ deficiency is for real and it happens in humans too

Mitochondrial transplants are successful but benefits are short lived

Lifespan.io (LEAF) - 25-Mar-2020

May be a solution to ageing related mitochondrial dysfunction which leads to diseases

Metastudy reviews impact of mitochondrial aging on cardiovascular disease

Lifespan.io (LEAF) - 18-Mar-2020

Still lots to discover, but SENS already looking at ways to stop it in its tracks

Cognitive and motor function improve with mitotherapy in aged mice

Fight Aging! - 06-Mar-2020

These are among other benefits revealing new insights into anti-aging research

How mitochondria drives senescence, affecting healthy ageing

EurekAlert! - 20-Feb-2020

Potential target for drug-based interventions to delay cellular ageing identified

NMN restores neurovascular health, improves cerebral blood flow in ageing

Lifespan.io (LEAF) - 17-Feb-2020

Mitochondria-targeted interventions in old mice could be key to age-related diseases.

Repletion of NAD+ has some degree of improvement on ageing in mice

Fight Aging! - 07-Feb-2020

Needs to study more on NAD+ interventions in order to achieve significant benefits

Hyperbaric oxygen therapy's impact on cardiac function

Jerusalem Post - 04-Feb-2020

Protocols were evaluated on the patients with “normal” aging heart

New discovery showed mitochondria found living in the blood

Lifespan.io (LEAF) - 27-Jan-2020

Mitochondria living in the blood definitely has some functions, further research needed to discover

How SENS is tackling mitochondrial DNA damage

Lifespan.io (LEAF) - 17-Jan-2020

Amutha Boominathan presented her work on MitoSENS project at Ending Age-Related Diseases 2019

An enzyme that prolongs lifespan in roundworms discovered

INVERSE - 07-Jan-2020

Results have been replicated in cultured human cells - a new hope for life extension?

Metabolism and mitochondria gene function impacted by spaceflight

New Scientist - 07-Nov-2019

Most changes reversed when back on Earth - but what about Mars microgravity?

Experimental drug reversed the fat build up in the liver

New Scientist - 02-Oct-2019

Tests done on animals suggest that CRMP reduces heart disease risk and animals didn't lose weight

From cryonic baths to ozone saunas, to the search of magic pill

Wired - 10-Sep-2019

In 2018 consumers spent $43 billion on anti-ageing products according to Orbis analysis

It's time for considering drug-exercise interactions

New York Times - 19-Jun-2019

Interesting - metformin plus exercise did not have an additive effect

Metabolite found in pomegranates has anti-ageing effects

Medical Xpress - 17-Jun-2019

Urolithin A could help slow certain aging processes, improve the functioning of mitochondria

Environmental pollutants in household items can affect ageing

INVERSE - 02-May-2019

Reduces length of telomeres and alters mitochondrial DNA levels in cells

Cellular aging halted by hydrogen sulfide gas

Medical News Today - 07-Aug-2018

3 compounds designed to deliver minute amounts of hydrogen to mitochondria inhibit cellular aging

Doctors Repair Infants’ Damaged Hearts With Mitochondria

Futurism - 10-Jul-2018

Procedure transplants mitochondria into infant’s muscle cells to prevent heart disease

Human Trial of Mitochondrially Targeted Antioxidant MitoQ

Fight Aging! - 20-Apr-2018

Inhibition of ageing maybe the solution for Alzheimer's

The San Diego Union-Tribune - 19-Jan-2018

Will be successful than drugs targeting specific aspects of Alzheimer's

Mitochondrial Contribution to Aging and Age-Related Disease

Fight Aging! - 21-Dec-2017

Boosting Mitochondrial Quality Control to Combat Alzheimer's

Lifespan.io (LEAF) - 08-Dec-2017

Key to Diseases in Mitochondrial DNA Mutations

Longevity Facts - 06-Dec-2017

SRF has made progress in the fight against ageing

Lifespan.io (LEAF) - 05-Dec-2017

R&D phase in SENS repair approach has shown promising results

High-intensity interval training (HIIT) Can Slow Aging

Care2 - 11-Sep-2017

Biologists slow ageing process in fruit flies

IB Times - 07-Sep-2017

British billionaire gambles on an anti-aging upstart

Endpoints News - 26-Jul-2017

Removing mutated DNA from mitochondria to turn back the aging clock

Caltech - 18-Nov-2016

Heavy Isotopes and Slowed Aging

Fight Aging! - 01-Sep-2016

Nicotinamide riboside (NR) stops the aging process in organs

Kurzweil Network - 06-May-2016

Mitochondria trigger cell aging

Medical Xpress - 04-Feb-2016

Review of Mechanisms that Slow Aging from Calorie Restriction

Fight Aging! - 06-Jan-2015