OpenAI's new AI model accelerates breakthroughs in longevity science

MIT Technology Review - 17-Jan-2025

Revolutionizing protein engineering to boost stem cells and combat ageing

Cyclarity Therapeutics advances to clinical stage with first-in-human trial

Biospace - 08-Jan-2025

A groundbreaking step toward disease-modifying treatments for cardiovascular care

New method turns tissue cells into heart cells for repair potential

Medical Xpress - 24-Dec-2024

The method uses vitamin C and FGF4 to make the cells work better

Turning colon cancer cells back to normal cells could revolutionise cancer therapy

KAIST - 23-Dec-2024

This could lead to safer, non-destructive cancer treatments with fewer side effects

New mRNA therapy could reverse signs of skin ageing

Live Forever Club - 20-Nov-2024

Scientists used mRNA therapy targeting ATF3 to rejuvenate skin

Unlocking the hidden potential of neural crest cells

Lifespan.io (LEAF) - 15-Nov-2024

Toronto researchers reveal neural crest cells' hidden role in direct lineage transitions

Cellular senescence surprisingly supports meniscus repair in rats

Live Forever Club - 05-Nov-2024

Early removal of these cells slows recovery, highlighting their short-term benefits

Cell reprogramming rejuvenates ageing neurons in mice

Medical Xpress - 24-Oct-2024

Scientists enhance brain function and protect against neurodegeneration

Unlocking cellular health: Booster therapeutics targets protein imbalance in ageing

Longevity Technology - 11-Oct-2024

New proteasome-activating drugs aim to tackle neurodegenerative diseases and extend healthy lifespan

Arda therapeutics pioneers new approach to combat chronic diseases and ageing

Longevity Technology - 10-Oct-2024

Targeted cell depletion offers a transformative strategy to treat diseases at their root

Stanford scientists unlock key to reviving ageing brain cells

SciTechDaily - 06-Oct-2024

Glucose regulation may hold the key to restoring neuron growth

TransVision Madrid 2024: pioneering longevity in Europe

Longevity Technology - 20-Sep-2024

Madrid becomes Europe's hub for advancing life extension and healthy ageing

The quest to rebuild the human brain

MIT Technology Review - 16-Aug-2024

A groundbreaking approach to extend life through brain tissue renewal

Partial reprogramming rejuvenates the ageing mouse brain, improving memory

Live Forever Club - 09-Aug-2024

This breakthrough offers hope for combating age-related cognitive decline

Harold Katcher on the development, results and future of E5

Live Forever Club - 07-Aug-2024

Now back in full control, Katcher is looking to market its topical application

New investigational drug shows promise in reversing age-related liver damage

Medical Xpress - 26-Jun-2024

Blocking cell death pathway rejuvenates livers in mice, offering potential treatment for humans

Reason reports back from Rejuvenation Startup Summit 2024

Fight Aging! - 13-May-2024

A great summary of 25 speakers who are in various stages of platform building, drug discovery and clinical trials

Seragon's anti-aging drug candidate extends healthspan and lifespan in mice

CISION PR Newswire - 07-May-2024

SRN-901 increases longevity gene expression and reduces aging activity

Jamie Justice provides an update on XPRIZE Healthspan competition entrants

Live Forever Club - 12-Mar-2024

Already over 200 organisations have pre-registered - this is going to be exciting to follow

The remaining lifespan of old mice, equivalent to a human age of 77 years, doubled

Live Forever Club - 25-Feb-2024

Therapy used OSKM genes to potentially extend lifespan and reverse ageing signs

Telomere-based interventions offer promising avenues for combating ageing

Live Forever Club - 23-Feb-2024

Telomere research is in its early stages, with much to be discovered

Lifespan.io speaks to Cyclarity’s CEO for an update on its novel atherosclerosis treatment

Lifespan.io (LEAF) - 19-Feb-2024

The company is developing a drug called UDP-003 to treat the disease

Scientists found a way to make old cells young again in a lab

Live Forever Club - 04-Feb-2024

They used special proteins to erase "marks" on DNA that build up with age

Mice regain vision through partial cellular reprogramming of retinal cells

Lifespan.io (LEAF) - 13-Dec-2023

While age ultimately caught up, study demonstrates potential of the novel treatment

UK biotech races US giants for longevity breakthrough

The Guardian - 05-Nov-2023

British researchers and startups vie to outpace tech billionaires in the fight against ageing

Eye-opening discovery: a potential non-invasive solution for age-related vision loss

Live Forever Club - 02-Aug-2023

Deglycating enzymes could offer an affordable, effective, and non-invasive treatment for presbyopia

Chemical cocktail able to reprogram cells to reverse ageing, without the need for gene therapy

Live Forever Club - 13-Jul-2023

David Sinclair and team discovers potential new approach to treat age-related diseases and promote healthy aging

Videregen seeks $10m funding for clinical trials of regenerated organs and tissues

Longevity Technology - 07-Jul-2023

Ground-breaking technology to advance the development of a bio-engineered thymus & lung disease treatments

FSU researcher and Lento Bio collaborate to treat age-related vision loss

Florida State University - 17-May-2023

Aims to cure presbyopia by restoring elasticity of the lens & inhibiting ageing process

Pioneering Heart Repair Technique: Reprogramming Adult Fibroblasts In Vivo

Lifespan.io (LEAF) - 25-Apr-2023

Potential for manipulating fibroblasts to improve heart healing and regeneration after heart attack

Life bio's gene therapy reboots cells, offering hope for vision loss and beyond

GlobeNewswire - 23-Apr-2023

Epigenetic reprogramming restored in primates, now paving way for human trials

Unveiling the future of age reversal: meet Yuri Deigin, founder of YouthBio Therapeutics

Longevity Technology - 08-Mar-2023

Tissue-specific gene therapies & rejuvenating factors to extend lifespan and combat age-related diseases

Neocortical grafting platform in brain repair

Live Forever Club - 07-Mar-2023

Multilayered architecture resulted in physiological and behavioural improvements. Could it help regenerate the ageing brain in future?

Partial Cellular Reprogramming in Very Old Mice Doubles Remaining Life Expectancy

Live Forever Club - 03-Feb-2023

Shown to work at a cellular level in humans, too, so a therapeutic could be developed soon

Dissociation of longevity targeted cell reprogram and somatic identity loss: An exploration

Live Forever Club - 17-Jan-2023

Most genes regulating cellular rejuvenation were not related to the increased occurrence of cancer

Focal Biosciences launched by PSI and Apollo Health Ventures

Business Wire - 11-Oct-2022

Aims to treat age-related diseases using advanced cellular reprogramming technologies

Therapeutic plasma exchange (TPE) rejuvenates multiple markers of gene expression

Lifespan.io (LEAF) - 25-Aug-2022

TPE causes systematic rejuvenation in human body by influencing multiple factors

mRNA delivers mutated proteins - regenerates cardiomyocytes post a heart attack

University of Houston - 16-Jun-2022

Stemin and YAP5SA notably restores normal cardiac pumping in mice

JuvLife Division raises 3.7 million euros for making antiaging product with Chrysea

Longevity Technology - 13-Jun-2022

Metabolites induce autophagy, stimulate cellular regeneration for healthy ageing

Lifespan.io interviews João Pedro de Magalhães about theories of, and curing, ageing

Lifespan.io (LEAF) - 13-May-2022

The one thing I hope he's wrong about is that it won't happen in his lifetime - we just need some exponential oomph!

YouthBio Therapeutics unveils its board, with João Pedro de Magalhães as CSO

CISION PR Newswire - 14-Apr-2022

Another company enters the cellular reprogramming race - hopefully at least one will cross the finishing line

Biological age of human skin cells reduced by 30 years (transcriptome and methylation clocks)

BBC - 08-Apr-2022

Transient reprogramming is progressing fast - how long before the first skincare product is launched?

Elastrin Therapeutics secures $10 million of funding for its calcification removal platform

Forever Healthy Foundation - 07-Apr-2022

Initially targeting stiffened arteries in cardiovascular disease, this could have wider implications

Long-term partial reprogramming reversed ageing process in mice

The Guardian - 07-Mar-2022

Yamanaka factors restored youthfullness in aged cells, raised hope for new anti-ageing therapies

Altos Labs comes out of stealth with $3 billion of capital

Genetic Engineering & Biotechnology News (GEN) - 19-Jan-2022

Huge backing that cellular reprogramming can have a significant impact on health and ageing

NewLimit, a new biotech launches to slowdown or reverse ageing

NewLimit - 12-Dec-2021

Aims to extend healthspan and cure ageing with affordable epigenetic therapies

Reversible reprogramming regenerates cardiac tissue after a heart attack

Endpoints News - 23-Sep-2021

Possibility of regeneration: A boon to the broad rejuvenation field

A promising approach to rejuvenate aged mesenchymal cells by chromatin

Medical Xpress - 13-Sep-2021

Short-term treatment of mesenchymal cells with acetate resulted to enhanced stem cell

Restoration of youthful gene expression can be achieved alternatively

Lifespan.io (LEAF) - 11-Jun-2021

Possible ways of using reprogramming techniques to develop therapies

Michael Greve promises 300m euros to advance rejuvenation startups

Longevity Technology - 06-May-2021

Kizoo Technology Ventures helps to bring rejuvenation therapies from lab to clinic

Brain cells reprogrammed to neurons within the brain of mice

Lifespan.io (LEAF) - 13-Apr-2021

In vivo conversion of astrocytes could possibly bring brain regeneration therapies in the near future

Reprogramming turns aged human cells young again

New York Times - 24-Mar-2021

Stanford University research published in New York Times - age-reversal is no longer fringe science!

SENISCA secures 1.3 million pounds to transform anti-ageing technology

University of Exeter - 12-Mar-2021

Spin out company from University of Exeter step forward towards precision medicine for age-related diseases

Elastrin's novel therapies to reverse age-related vascular damage

Longevity Technology - 04-Mar-2021

Advancing technologies for tissue and organ rejuvenation with seed funding from Kizoo

Goya et al review progress in cell reprogramming

Live Forever Club - 24-Feb-2021

Considers whether, and impact if, epigenetic clock is one component of a modular ageing mechanism

Protein that regulates muscle function in ageing discovered

Stanford School of Medicine - 10-Dec-2020

Blocking it improved muscle strength & function while endurance was also boosted in mice

Vision loss due to age & glaucoma reversed in mice

Medical Xpress - 02-Dec-2020

David Sinclair says findings are 'transformative for the care of age-related vision diseases'

Memory retrieval made possible with a resetting drug

Medical Xpress - 01-Dec-2020

An experimental drug restores age related memory loss and brain function in mice

Skin regeneration reactivated in adult mice

Medical Xpress - 29-Sep-2020

New skin was able to produce fur - might eventually become a treatment for baldness, who knows

LEAF interviews the Conboys about rejuvenating mice by diluting blood plasma

Lifespan.io (LEAF) - 16-Jun-2020

This could be a cheap first generation rejuvenation treatment - but wait for clinical trials

ThirdLaw may have designed a way to break crosslinks to reverse tissue ageing

Longevity Technology - 29-May-2020

Whoever controls the shape of a molecule controls what it can do

Fountain secured $6 million Series A-1 financing from Khosla Ventures

GlobeNewswire - 19-May-2020

With a total of $11 million, more in vivo preclinical drug testing to be expected

Mice vision restored by reprogramming fibroblasts to photoreceptors

Lifespan.io (LEAF) - 21-Apr-2020

Important study in developing cheap and effective treatments for retinopathies

A new faster technique restores vision in mice with retinal degeneration

National Institutes of Health (NIH) - 15-Apr-2020

Researchers plan clinical trials of this in humans to treat retinal diseases

Donor supercentenarian’s cells help unlock mysteries of super-longevity

Longevity Technology - 28-Feb-2020

Evidence of cellular age reversal demonstrated in this gateway research

NAD+ replenishment improves and restores fertility in women

Lifespan.io (LEAF) - 24-Feb-2020

This provides simple, safe way to rejuvenate egg cells as shown in aged mice study

LEAF interviews Hanadie Yousef, co-founder and CEO of Juvena Therapeutics

Lifespan.io (LEAF) - 11-Feb-2020

Muscle regeneration would have a huge hit on healthspan - getting people more mobile again

Novo Biosciences CEO talks about drug candidate for tissue regeneration

Lifespan.io (LEAF) - 29-Oct-2019

Regrowing damaged organs would help many people live longer, healthier lives

British and Israeli teams join to reverse ageing of blood vessels

British Heart Foundation - 25-Oct-2019

British Heart Foundation working on anti-ageing research? It must be mainstream now!

LEAF interviews AgeX Therapeutics CEO Dr. Michael West

Lifespan.io (LEAF) - 30-Sep-2019

May only be a few years away from implementing induced tissue regeneration in humans

Lysoclear is making progress towards a cure for macular degeneration

Lifespan.io (LEAF) - 25-Sep-2019

Has cleared protein build up in vivo - has funding to develop clinical candidates

Michael West examines how to safely revive telomerase

Lifespan.io (LEAF) - 12-Sep-2019

It powers foetal development and telomere length, but also cancers

Reversing epigenetic changes rejuvenated mice with progeria

MIT Technology Review - 08-Aug-2019

Could turning back the clock on genes make us live much longer?

Adult neurons can grow with the help of a group of proteins

Medical Xpress - 07-Aug-2019

Potential to cure paraplegia and quadriplegia someday in the future

Chemicals identified to reverse mental decline

BBC - 14-Feb-2019

Mental capacity not lost - just masked by inflammation

Mini-thymus used to produce and train T cells

Lifespan.io (LEAF) - 21-Jan-2019

Able to regenerate ageing immune system, and reduce cost of immunotherapy

Cells of living mice rejuvenated using OSKM trigger in drinking water

Lifespan.io (LEAF) - 17-Jan-2019

More support for the SENS approach of regular maintenance to stop ageing

Oral treatment for wet age-related macular degeneration passes Phase 2a trials

CISION PR Newswire - 17-Dec-2018

Intriguing hint that this treatment may have potential for other age-related diseases

Reversing aging by removing wrinkles inside our cells

ScienceDaily - 29-May-2018

Virus-based treatment seeks to smooth cellular wrinkles in livers

XPO1 inhibition increases autophagy and lifespan

News Medical - 16-May-2018

This treatment could be used to alleviate neurodegeneration and disease progression

Can autophagy boost your health?

BBC - 06-May-2018

Scientists decipher mechanisms underlying the biology of aging

Phys.org - 02-Nov-2017

Protein Signalling Implicated in Age-Related Hair Graying

Fight Aging! - 25-Oct-2017

Rejuvenating the Thymus to Prevent Age-related Diseases

Lifespan.io (LEAF) - 04-Oct-2017

Scientists develop a chip that can regenerate damaged tissue

Scientific American - 29-Sep-2017

Can it convert only specific target cells?

SRF to develop glucosepane-cleaving antibodies with Spiegel Lab

Lifespan.io (LEAF) - 17-Sep-2017

Anti-glucosepane antibodies may offer new therapies for age-related diseases

BioTime's CEO: Human Aging Will Soon Become a Thing of the Past

Mauldin Economics - 06-Jun-2017

Treating Diseases with a Protein Missile System

Lifespan.io (LEAF) - 26-May-2017

Repairing Mitochondrial DNA for Age-related Diseases

Lifespan.io (LEAF) - 02-May-2017

Induced Pluripotency to Enable Rejuvenation of Blood Production

Fight Aging! - 23-Feb-2017

Exciting Therapy To Treat Age Related Blindness Moving To The Clinic

Lifespan.io (LEAF) - 15-Feb-2017

Fight Aging predicts the sequence of arrival for meaningful antiaging therapies

Next Big Future - 01-Dec-2016

DNA repair and metabolism as determinants of species longevity

eLife Sciences - 22-Nov-2016

Scientists to ‘reset’ blood proteins in attempt to slow ageing process

Guardian - 22-Nov-2016

Removing mutated DNA from mitochondria to turn back the aging clock

Caltech - 18-Nov-2016

Mechanotherapy regenerates injured muscle tissue

Kurzweil Network - 28-Jan-2016

Self assembling biological tissue-like material grown in lab

Queen Mary University of London - 28-Sep-2015

3D-printed guide helps regenerate complex nerves

Kurzweil Network - 18-Sep-2015

Investigating the Mechanisms of Remyelination

Fight Aging! - 07-Sep-2015

Rejuvenation Biotechnology 2015 : Thoughts on Thymus Regeneration

Fight Aging! - 24-Aug-2015