Metformin: does it really slow ageing in animals, or just help health?

SENS Research Foundation - 12-Oct-2024

Despite positive results in monkeys, study lacks baseline data, which raises doubts

Common prescription medications can affect how long people live

Live Forever Club - 11-Oct-2024

Metformin (HR 1.01, CI 0.95–1.07) had a neutral effect on mortality

Diabetes drug metformin shows promise in slowing brain aging in monkeys

Nature - 12-Sep-2024

New study reveals metformin’s potential to delay brain aging

Metformin may minimize muscle loss in extended periods of bed rest

Lifespan.io (LEAF) - 24-Jul-2023

Improvements seen in muscle size and collagen deposits in older people with atrophy

Diabetes medication metformin could lower long COVID risk by 41%, study suggests

New Scientist - 09-Jun-2023

Metformin may function as an anti-inflammatory and potentially reduce the viral load of SARS-CoV-2

Unraveling the long-term impacts of metformin on lifespan: a 20-year study

Live Forever Club - 16-May-2023

Extensive analysis reveals an initial benefit to longevity that diminishes, then reverses, over time

Peter Attia comments on Danish metformin study that does not find benefit to general population

Peter Attia website - 11-Mar-2023

Original study was subject to bias due to exclusion of participants who progressed to multiple therapies

Metformin misinterpreted as antiaging drug via animal studies, TAME heads for future trials

SENS Research Foundation - 04-Oct-2022

More than 90% of drugs safe and effective when tested in experimental animals fail in human testing

NIH awarded OMRF $3 million to study anti-aging abilities of a diabetic drug

Oklahoma Medical Research Foundation (OMRF) - 13-Jul-2022

Investigation of ability of metformin, a diabetic drug to slow the process of aging

Lifespan.io interviews Dr. Nir Barzilai about metformin, longevity genes and more

Lifespan.io (LEAF) - 29-Jun-2021

Optimistic on ageing research and a breakthrough human trial to extend healthspan

Has Metformin received too much of an attention as an anti ageing drug?

Fight Aging! - 14-Jan-2021

Studies show promise with metformin - tiny positive outcomes with side effects

Age limits health span benefits of metformin in worms

Medical Xpress - 12-Nov-2020

Scientists link metformin toxicity with age in young,old non diabetic organisms

Metformin with Resistance Training- To do or not to do?

Lifespan.io (LEAF) - 29-Oct-2020

Metformin might inhibit muscle building but makes gene expression more youthful

Josh Mitteldorf on monitoring blood glucose while taking metformin and berberine

Aging Matters - 31-Aug-2020

Eating habits and exercise alter blood glucose levels - wearables may help get a rough idea

Bayshore latest drug maker to recall metformin after carcinogens found

FiercePharma - 21-Aug-2020

A good example of why you have to be careful buying meds - even big pharma has problems.

Crowdsourced samples of metformin from USA contain unacceptable levels of NDMA

New York Times - 27-May-2020

Found only in extended-release versions of metformin, immediate-release versions are okay

Metformin alleviates inflammaging by promoting autophagy

Lifespan.io (LEAF) - 14-May-2020

With the positive results, drug holds great promise for promoting healthy ageing

Metformin repairs metabolic and mitochondrial defects in myotonic dystrophy

Lifespan.io (LEAF) - 16-Apr-2020

New hope for sufferers of disorders that negatively impact metabolism

Can we treat the ageing process or not? That's the question

UCSF - 02-Jan-2020

John Newman, UCSF asst prof & Buck Institute researcher, explains upcoming ageing interventions

Calorie restriction can restore myelin on demyelinated nerves

Lifespan.io (LEAF) - 22-Nov-2019

Tested in mouse model - but it's a good starting point

US doctor opens online anti-ageing clinic

CNBC - 06-Oct-2019

We need proactive longevity doctors in the UK to advise on best approaches at an individual level

Reason analyses a new review paper on metformin - he's not keen

Fight Aging! - 27-Sep-2019

There have been more negative results in mice than positive - surprising given the press it gets

Biological age reversed with growth hormone and diabetes drugs cocktail

Nature - 05-Sep-2019

Small, uncontrolled trial, but (potentially) very exciting results

World's first anti-ageing trial received FDA approval

Longevity Technology - 04-Sep-2019

TAME trial lead by clinician Dr Nir Barzilai will begin in November

Metformin gives diabetics longer life than non-diabetics

AGEIST - 03-Mar-2019

Great summary of the drugs history, benefits and risks

David Sinclair's admits taking NMN, resveratrol and Metformin

Next Big Future - 01-Feb-2019

Nothing too surprising in his daily supplement regime

Ray Kurzweil talks about Physical Immortality

Aging Reversed - 03-Jan-2017

Metformin, Gamma Rays or Chocolate?

Institute for Ethics and Emerging Technologies (IEET) - 26-Dec-2015

Metformin human trials planned

Diabetes.co.uk - 30-Nov-2015

Metformin seeks approval for first life extension drug trial

City AM - 09-Jul-2015

Survival benefits of metformin in non-diabetics: faulty analysis in a 2014 study

Science Media Centre - 08-Aug-2014

It's not logical to advise people without diabetes to take metformin