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Lifespan Research Institute (LRI)

Supporting the development of biotechnologies focused on ending age-related diseases, previously known as Lifespan.io

Lifespan Research Institute is a 501(c)3 non-profit organization focused on developing, promoting, and ensuring widespread access to regenerative medicine solutions targeting the disabilities and diseases of aging, combining direct research efforts with robust education, affiliation, and outreach programs.

In addition to intramural research programs, Lifespan Research Foundation supports research projects at universities and institutes around the world with the goal of curing such age-related diseases as macular degeneration, heart disease, cancer, and Alzheimer’s disease.

Educating the public about how we can solve the economic and political issues stemming from an aging world population and training researchers to support a growing regenerative medicine field are also major endeavors of the organization that are being accomplished though advocacy campaigns and educational programs.

Lifespan Research Institute is dedicated to ensuring that the benefits of longevity research are accessible on the international stage, with the aim of creating a future where everyone has access to biomedical advancements.

Previously known as Life Extension Advocacy Foundation and lifespan.io.

In October 2024, two pioneering groups joined forces. The SENS Research Foundation merged with the Lifespan Research Institute.

Initial founders:

  • Keith Comito
  • Oliver Medvedik
  • Richard Kaufman
  • Apneet Jolly

Visit website: https://www.lifespan.io/

 LifespanResearchInstitute

 lifespanresearchinstitute

 LifespanRI

 lifespanio

Details last updated 22-Aug-2026

Lifespan Research Institute (LRI) News

The science behind Urolithin A and how it helps our cells age better

The science behind Urolithin A and how it helps our cells age better

Live Forever Club - 20-Oct-2025

Natural compounds may help keep our bodies healthier for longer

Targeting ageing cells: LAMP1 emerges as a key senescence biomarker

Targeting ageing cells: LAMP1 emerges as a key senescence biomarker

Lifespan.io (LEAF) - 14-Mar-2025

LAMP1 may help distinguish and eliminate harmful senescent cells in age-related diseases

Reason reviews progress made in ageing research and potential rejuvenation treatments

Reason reviews progress made in ageing research and potential rejuvenation treatments

Fight Aging! - 31-Dec-2024

Biotech industries and ageing clocks offer new ways to tackle ageing

Two longevity organisations join forces to tackle the biology of ageing

Two longevity organisations join forces to tackle the biology of ageing

Longevity Technology - 09-Oct-2024

SENS and Lifespan.io unite research and public outreach under one roof

Dr. Sajad Zalzala reports on PEARL rapamycin trial results

Dr. Sajad Zalzala reports on PEARL rapamycin trial results

Live Forever Club - 28-Aug-2024

Safety of rapamycin looks good and lean muscle mass among biomarkers trending towards improvement

Lifespan.io crowd-funds clinical trial to determine the effects of Rapamycin

Lifespan.io crowd-funds clinical trial to determine the effects of Rapamycin

Lifespan.io (LEAF) - 17-May-2021

PEARL: Participatory Evaluation of Aging with Rapamycin for Longevity

Irina Conboy explains latest blood plasma dilution results to lifespan.io Journal Club

Irina Conboy explains latest blood plasma dilution results to lifespan.io Journal Club

Live Forever Club - 27-Jan-2021

Conboys are planning a modified lifespan study - looking for funding

Major mouse senolytics testing experiment is go!

Major mouse senolytics testing experiment is go!

Lifespan.io (LEAF) - 13-Apr-2020

We'll almost certainly need a combination of drugs so look forward to seeing the results

Interview with LEAF's Elena Milova

Interview with LEAF's Elena Milova

Medium - 09-Jan-2020

Education and funding are essential to enable radical life extension in the next 20 years

Developmental stages of anti-ageing treatments

Developmental stages of anti-ageing treatments

Next Big Future - 09-Jun-2019

Two anti-ageing treatments in phase 3 clinical trials and four in phase 2 clinical trials

Crowdfunding NAD+ Mouse Lifespan Study

Crowdfunding NAD+ Mouse Lifespan Study

Lifespan.io (LEAF) - 18-Sep-2018

This project aims to observe if the NAD+ precursor has a positive effect over aging mice

Mentioned in this Resource

SENS Research Foundation

Non-profit organization focused on transforming the way the world researches and treats age-related diseases

Lifespan Research Institute (LRI) is also referenced in the following:

SENS Research Foundation

Non-profit organization focused on transforming the way the world researches and treats age-related diseases

Lifespan Research Institute (LRI) Blog Posts

Highlights of Ending Age-Related Diseases 2020
10-Sep-2020

Highlights of Ending Age-Related Diseases 2020

Key points from 20 presentations from world-leading researchers

Lifespan Research Institute (LRI) Creations

A Summary of Spermidine

lifespan.io summarises how it is created and the latest research into its geroprotective properties

Ending Age-Related Diseases 2023

10-Aug-2023 to 11-Aug-2023

Longevity+DeSci Summit NYC brings the best longevity researchers and biotech investors together organized by Lifespan.io

Why Political Action Matters for Longevity - Dylan Livingston at Ending Age-Related Diseases 2022

Dylan Livingston of the Alliance for Longevity Initiatives explains why political longevity activism needs to exist (YouTube)

Ending Age-Related Diseases 2022

11-Aug-2022 to 14-Aug-2022

Virtual Conference for Rejuvenation Biotechnology and Life Extension organized by Lifespan Extension Advocacy Foundation

Major Mouse Testing Program

Program that used mice to research senolytic and its impact on aging

Ending Age-Related Diseases (EARD) 2021

19-Aug-2021 to 22-Aug-2021

Hear the latest developments from the leading experts in rejuvenation biotechnology research

Ask Me Anything (AMA) with The PEARL Team

28-May-2021

Find out more about the Participatory Evaluation of Aging with Rapamycin for Longevity Study (FREE)

Other people at Lifespan Research Institute (LRI)

Anna Drangowska-Way

Science writer at Lifespan.io

Stephanie Dainow

Executive Director at Lifespan.io (Lifespan Extension Advocacy Foundation)

Larisa Sheloukhova

Staff writer at LEAF, longevity advocate

Tovah Wolf

Consultant Dietitian, Science Communication, Nutrition Counselor, Educator

Javier Noris

Founder and VC at ScienceVest.

Tim Maupin

Director and Cinematographer.

Keith Comito

President at Life Extension Advocacy Foundation.

Oliver Medvedik

Director of The Maurice Kanbar Center for Biomedical Research and Vice President of LEAF.

Sedeer el-Showk

Science writer

Arkadi Mazin

Journalist, Lifespan.io

Steve Hill

Editor in Chief and Director of the board at LEAF