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Inflammaging News

TRexBio raises $84M to develop immune therapies targeting inflammation

Longevity Technology - 20-Nov-2024

Funding strengthens their capacity to address unmet needs in immune-related diseases

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Stem cell therapy shows promise in slowing ageing and preventing disease

Newsweek - 29-Sep-2024

Mesenchymal stem cells may revolutionize healthcare by combating inflammation and ageing

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Healthy centenarians have lower NLRP3 levels, protecting them from ageing effects

Live Forever Club - 11-Sep-2024

NLRP3 is a part of immune system that plays a key role in chronic inflammation

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Metabolomics reveals key metabolic changes associated with ageing and frailty

Live Forever Club - 20-Aug-2024

This could lead to improved diagnostics and therapies for frailty

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Urolithin A, a natural compound, could be a key player in promoting healthy ageing

Live Forever Club - 04-Aug-2024

It enhances mitochondrial health, but does not significantly increase ATP

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Natural peptide restores immune balance, reversing age-related inflammation

Medical Xpress - 18-Jul-2024

PEPITEM supplementation shows promise for extending healthy lifespan

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Breakthrough drug extends lifespan of mice by 25% - safety already demonstrated in humans

BBC - 17-Jul-2024

Interleukin-11 antibody shows promise as an anti-ageing treatment that could revolutionise human longevity

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Midlife inflammation, even in healthy people, slows down walking speed in later life

Live Forever Club - 21-Jun-2024

The longer the inflammation lasted, the slower the walking speed became

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Cell malfunctions can cause information leakage and trigger inflammation

University of Virginia School of Medicine - 05-Mar-2024

The discovery may improve inflammation treatment and anti-ageing interventions

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Anti-inflammatory benefits: fasting found to reduce risk of many diseases

University of Cambridge - 30-Jan-2024

Calorie restriction silences the NLRP3 inflammasome, a key driver of inflammation

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Once helpful immune alarm bells, inflammasomes now fuel chronic diseases

Live Forever Club - 18-Jan-2024

Researchers are developing new treatments to turn down the inflammatory response

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Halia Therapeutics' NLRP3 inhibitor shows promise in tackling chronic inflammation

Longevity Technology - 11-Jan-2024

Shown promising results in preclinical studies and early clinical trials

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Forward therapeutics secures $50m to develop next-gen small molecule immune therapies

Longevity Technology - 09-Nov-2023

Company's pipeline targets inflammation, promote healing, and restore quality of life

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Summary of Daniel E. Martin-Herranz presentation at Longevity Med Summit

Live Forever Club - 18-May-2023

Building a saliva-based epigenetic biomarker for systemic chronic inflammation (SCI)

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Challenging Inflammaging in the Pursuit of Healthy Ageing

Live Forever Club - 24-Feb-2023

Chronic inflammation is lurking behind many age-related diseases, but also offers up many targets to reduce it

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Lifespan.io interviews NaNotics' CEO Lou Hawthorne to find out more about Nanots

Lifespan.io (LEAF) - 04-Nov-2022

Many conditions could be improved by removing signalling that prevents cells operating at their best

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Phase 2 clinical trial of lead drug candidate MYMD-1- a therapy for delaying aging

Business Wire - 26-Jul-2022

Sarcopenia drug trial shows no evidence of toxicity or safety issues

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Study in mice says faecal transplants could possibly reverse ageing

University of East Anglia (UEA) - 04-May-2022

Gut microbiome dictates and decides the health of your gut, eyes, and brain

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Limiting calories rewires immuno-metabolic function for longer healthspan in humans

GEN News - 14-Feb-2022

Protein produced by macrophages was identified as a key player of calorie restriction

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ChromaDex releases results of clinical trial demonstrating anti-inflammatory effects of NR

Longevity Technology - 28-Jan-2022

Gold-standard trial included 35 participants taking 1000mg of NR (or placebo) for a week

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MyMD Pharmaceuticals begins phase 2 trial of TNF-inhibitor in January 2022

Longevity Technology - 14-Dec-2021

Potential oral treatment to prevent sarcopenia and frailty, and extend healthy lifespan

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New CRISPR based stem cell implant releases drug as required in arthritis

GEN News - 02-Sep-2021

Reduced inflammation & bone damage in mice; relieves patients from their regular use of injections

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Hyperactivation of senescent cells can trigger cytokine storm

Lifespan.io (LEAF) - 13-Aug-2021

Stimulated senescent human umbilical vein cells showed high susceptibility to inflammatory diseases

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Skeletal stem cells delay bone healing and foster inflammageing in older people

Medical Xpress - 12-Aug-2021

Treating with BMP2 and Csf1 antagonist in mice restored youthfulness to the aged skeletal system

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Stem cell therapy: A potential avenue for reversing pituitary gland ageing

Medical Xpress - 15-Jun-2021

Slowing down natural ageing process of pituitary glands with stem cells

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Can short-term immune memory impact longevity?

Medical Xpress - 11-Feb-2021

Less inflammation due to shorter immune memory prolonged life of blind mole rats

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Proteins from parasitic worms could be the next anti-ageing therapy

Science Daily - 02-Feb-2021

Helminth parasites may provide protection against inflammation disorders

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Lab-grown human muscle showed benefits of exercise

INVERSE - 29-Jan-2021

Tissue engineered muscle under simulated exercise prevented chronic inflammation

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New evidence on reversing cognitive ageing in aged mice

The Scientist - 20-Jan-2021

EP2 receptor which causes inflammation & ageing was knocked down in a disease model

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A force of tissue stiffness could bring new changes to immune drugs

Buck Institute - 12-Jan-2021

Tissue stiffness alter immune system response to chronic diseases and ageing

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Early intervention before disease progression using glyhealth

Longevity Technology - 08-Dec-2020

Avenna's glyhealth alerts practitioners about subclinical chronic inflammation

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Hidden inflammapath in your mouth invites deadly diseases

Longevity Technology - 25-Nov-2020

Keystone Bio's first ever biologic on the planet to eliminate oral pathogen

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Chronic inflammation promotes NAD+ decline during aging

Buck Institute - 16-Nov-2020

Senescent cells induce NAD+ decline via activation of CD8 macrophages

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Walnut - a super nut for a healthy heart

Genetic Engineering & Biotechnology News (GEN) - 10-Nov-2020

Decreases chronic inflammation and the risk of cardiovascular disease

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OTC drug Ibuprofen could reverse age associated inflammation

Longevity Technology - 06-Nov-2020

A study on mice supported ibuprofen for use in neurodegenerative diseases

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Scientists discover a life threatening inflammatory disease

WorldHealth.Net - 27-Oct-2020

Called VEXAS- discovered using a novel genome first strategy

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Anti inflammatory peptides discovered in rice using Nuritas' AI program

Longevity Technology - 03-Sep-2020

Peptides reduce inflammaging and improve standardised physical tests

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Body builder supplement AKG extends lifespan and healthspan of mice

Buck Institute - 01-Sep-2020

Blood levels fall with age. NUS planning a clinical trial with middle-aged humans.

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Low stress hormone levels promotes premature ageing

Longevity Technology - 11-Aug-2020

Balance is key to everything especially with human body

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Cohort study: Glucosamine reduces mortality by 15%

Fight Aging! - 28-Jul-2020

Supplementation with this anti-inflammatory drug can give us more benefits than we know

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A novel cell therapy to reverse age related impairments

Science Daily - 06-Jul-2020

Physical fitness and immune health restored in aged mice models

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Low cortisol levels can trigger 'macrophaging'

Medical Xpress - 01-Jul-2020

Learning this age-induced disruption of macrophage functions powers pharmaceutical research

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Scientists found a link to balance immunity and longevity

Max Planck Society - 24-Jun-2020

Gene changes in round worm lead an interesting evidence to longevity

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The effect of gut microbiota on cognitive decline in aged rats

Fight Aging! - 14-May-2020

First study investigating its effects in the normal ageing process

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Metformin alleviates inflammaging by promoting autophagy

Lifespan.io (LEAF) - 14-May-2020

With the positive results, drug holds great promise for promoting healthy ageing

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Altering macrophage epigenetics to prevent lumbar disc degeneration

Lifespan.io (LEAF) - 04-May-2020

Findings can lead future treatments for age-related conditions caused by inflammaging

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Reducing Inflamm-Aging by topical skin application, beneficial in chronically aged

University of California, San Francisco (UCSF) - 13-Mar-2019

Rejuvenating the skin can reverse “inflamm-aging may have profound health effects

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