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Alzheimer's Disease News

Abbvie’s $1.4b bet on alzheimer’s biotech Aliada

Longevity Technology - 29-Oct-2024

Aliada’s BBB technology aims to transform CNS drug delivery

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NHS rejects funding for new Alzheimer's drug due to small benefit, high cost

BBC - 23-Oct-2024

The drug 'donanemab' remains available for private treatment in England

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Analysis of 1.6 million brain cells uncovers key Alzheimer’s disease pathways

Columbia University Irving Medical Center (CUIMC) - 28-Aug-2024

It provides insights into the disease and suggests new prevention strategies

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Scientists unveil genetic secrets to sharp minds in centenarians

PsyPost - 07-May-2024

Protective gene variants in immunity & cellular cleanup prevent Alzheimer's in old age

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APOB protein may shorten healthy lifespan and increase Alzheimer's risk

Live Forever Club - 16-Mar-2024

Providing a promising target for interventions aimed at promoting healthy ageing

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20-year study maps Alzheimer's progression, offering hope for early detection

Live Forever Club - 29-Feb-2024

Researchers tracked changes in brains, including protein levels & brain shrinkage

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Alector doses first patient in Alzheimer’s trial for new therapy

Alector - 08-Feb-2024

Al101 shows promise in boosting brain health for early Alzheimer’s patients

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Biogen discontinues controversial Alzheimer's drug Aduhelm

Independent - 31-Jan-2024

Once hailed as a breakthrough, Aduhelm faces final curtain after limited use and insurance hurdles

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Simple blood test spots Alzheimer’s 15 years before symptoms

Independent - 22-Jan-2024

This could pave the way for routine screening of individuals over 50

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New app catches hidden Alzheimer’s signs that most tests miss

Inside Precision Medicine - 19-Dec-2023

This app could help identify those at risk sooner for timely intervention

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Natural killer cell therapy combats Alzheimer's disease in phase 1 trial

Medscape - 02-Nov-2023

Enhanced immune cells target inflammation and protein buildup, offering cognitive improvements

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Gut bacteria linked to Alzheimer's disease in groundbreaking study

King's College London - 17-Oct-2023

Research findings may lead to new treatments for the most common cause of dementia

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UK biotech startup Astronautx raises $61M to tackle neurodegenerative diseases

Longevity Technology - 11-Oct-2023

Aims for Alzheimer's drugs that target brain's predominant cells, astrocytes

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Longeveron's Lomecel-B shows promising effects in Alzheimer's trial

Longeveron - 05-Oct-2023

New breakthrough cell therapy offers potential for slowing disease progression

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Phase I trial shows early promise in clearing senescent cells in Alzheimer's

Wake Forest Baptist Health - 07-Sep-2023

The treatment was well-tolerated with no significant changes in brain function

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Voyager's new gene therapy targets amyloid plaques in Alzheimer's disease

FierceBiotech - 04-Aug-2023

New treatment approach could be more effective in lowering the risk of serious side effects

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Experimental vaccine promises to slow down or prevent Alzheimer's in mice

American Heart Association - 30-Jul-2023

Vaccine not only reduced inflammation, but also improved behavior and awareness in mice

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Donanemab slows Alzheimer’s disease in trial, but with serious side effects

New Scientist - 18-Jul-2023

New Alzheimer's drug benefits early-stage patients; concern remain about affordability and serious risks

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Covalent Bioscience's catabodies could transform Alzheimer’s treatment

Medium - 08-Apr-2023

Company is seeking funds to advance from preclinical tests to human trials

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Gut microbiome linked to brain damage and neurodegeneration in mice

EurekAlert! - 12-Jan-2023

Modifying gut microbiota with antibiotics reduced inflammation and tau-linked damage

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In silico drug repurposing method and insurance data analysis identifies Sildenafil as potential therapy for Alzheimer’s disease

Live Forever Club - 06-Dec-2022

Current research identified drug candidate, big data analysis confirmed an association, and lab work demonstrated a biological effect

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Medin- amyloid-β aggregates could act an new targets to therapeutically treat Alzheimer's

German Center for Neurodegenerative Diseases (DZNE) - 17-Nov-2022

Medin deposits are indeed a cause of blood vessel damage, one of the causes of Alzheimer's disease

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Eisai's Lecanemab drug proves to slowdown Alzheimer's disease, unlike aducanumab drug

BBC - 28-Sep-2022

Historic moment for dementia research-large clinical trial to successfully slow cognitive decline

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Alzheimer’s disease can be treated in blood circulation instead of in the brain

UTHealth - 14-Jul-2022

A target for Alzheimer’s disease therapy may lie in plasmapheresis or blood dialysis

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FDA-approved psychiatric drugs may help improve cognitive symptoms

University of Colorado Anschutz Medical Campus - 29-Jun-2022

Imipramine or olanzapine block APOE4 and reverses Alzheimer’s disease

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Oral rapamycin aggravates Alzheimer's associated beta-amyloid plaques in mice

Medical Xpress - 07-Jun-2022

Cautioned the use of rapamycin in Alzheimer's patients, as it downregulated Trem2 & reduced β-amyloid clearance

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Prothena's anti-amyloid therapy receives FDA fast track designation to treat Alzheimer’s

BioPharma-Reporter - 03-May-2022

Guarantees higher efficacy, convenience and potential safety than other anti-Aβ therapies

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Alzheimers' treatment with stem cells is proven safer in Phase 1 clinical trial

Lifespan.io (LEAF) - 07-Apr-2022

Lomecel-B targets homing and microglia recruitment rather than differentiation

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Altoida raised $14 million to advance a smart platform for Alzheimer's detection

Washington Business Journal - 28-Mar-2022

The approach may make testing more accessible for those without specialist healthcare access

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Irregular sleep-wake cycle may increase the risk of Alzheimer’s disease

The Guardian - 10-Feb-2022

24-hour circardian regulation and good sleep hygeine can possibly delay the onset of dementia

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AMBAR study improved the quality of life in Alzheimer's disease

Lifespan.io (LEAF) - 12-Nov-2021

A hot topic in longevity research is plasma exchange for Alzheimer’s disease

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Reversing dementia in mice sets stage for human clinical trials

New Atlas - 29-Jun-2021

SAK3, the first compound to target the activity in neurodegenerative disorders

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For the first time in 20 years, FDA approved new drug to treat Alzheimer's disease

BBC - 08-Jun-2021

A long way from a cure, but hopefully indicates that Alzheimer's isn't unassailable

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Gene therapy preserved memory and learning in mice with Alzheimer's

Lifespan.io (LEAF) - 11-May-2021

Boosting a vital protein, Caveolin-1, this new technique offers hope against neurodegenerative diseases

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Gene therapy for Alzheimer's disease enters human clinical trial

Forbes - 12-Mar-2021

Virus carries gene encoding protein into the brain -possible breakthrough treatment for neurodegenerative diseases

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Experimental Alzheimer's drug improved cognition and behavior

BioWorld - 02-Feb-2021

With positive results in phase 2b, simufilam to begin phase III in second half of 2021

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New evidence on reversing cognitive ageing in aged mice

The Scientist - 20-Jan-2021

EP2 receptor which causes inflammation & ageing was knocked down in a disease model

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Eli Lilly's Alzheimer's drug passed phase 2 trial

Eli Lilly and Company - 11-Jan-2021

Clears plaque and slows clinical decline in patients with early-stage Alzheimer's

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Re:Cognition Health is running Alzheimer’s disease clinical trials

Plymouth Live - 27-Nov-2020

Looking for volunteers in Plymouth area - travel expenses reimbursed

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Changes in retina could help identify Alzheimer's

Cedars-Sinai - 17-Nov-2020

Identifying early changes will help diagnose patients early and treat better

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$2M granted for clinical trial of Rapamycin in Alzheimer's

UT Health San Antonio - 25-Aug-2020

People are now willing to say that treating ageing might help ameliorate age-related diseases

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Synthetic fisetin used to identify new target in fight against Alzheimer's

New Atlas - 05-Aug-2020

CMS121 lowered levels of fatty acid synthetase (FASN) which inhibited lipid peroxidation

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Blood test for detecting Alzheimer's before symptoms appear

BBC - 29-Jul-2020

Experts found a protein indicating the disease, providing early treatment in the future

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Even one flu shot may reduce your chance of getting Alzheimer's

UTHealth - 27-Jul-2020

This certainly is not a plus point for the anti-vaxx movement

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Scientists find a new and easy way of producing neurons

Science Daily - 25-Jun-2020

PTB is the ultimate switch that controls conversion of a cell into a neuron

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Flavonoids in fruits, red wine and tea might protect your brain from dementia

WebMD - 13-May-2020

Reduce the risk of getting dementia by two to four folds

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Simple blood testing to detect Alzheimer's disease

Futurity - 12-May-2020

This discovery could greatly reduce costs of diagnosing and studying the disease

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How external factors could influence Alzheimer’s disease via the gut microbiome

Lifespan.io (LEAF) - 20-Apr-2020

Early study into complex neurochemical relationship between brain, gut and inflammaging

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Nanoparticles containing curcumin can be a solution for Alzheimer's

Science Daily - 05-Mar-2020

Curcumin when encapsulated in nanoparticles, gets better absorbed

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Dietary intake of flavonols may reduce risk of having Alzheimer's dementia

NHS - 03-Feb-2020

Balanced diet, physical and mental exercise, still key to lowering dementia risks

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AlzEye to hunt for Alzheimer's in retina scans

The Economist - 18-Dec-2019

People's eye changes over 10 years were correlated with the emergence of Alzheimer’s disease

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Alector’s AL002 shows early promise in Alzheimer’s treatment

Biospace - 09-Dec-2019

First-in-human trial demonstrates safety and brain-target engagement for TREM2 therapy

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First therapy that could slow Alzheimer's disease

BBC - 22-Oct-2019

Groundbreaking drug is called aducanumab, which targets a protein called amyloid

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NeuroEM develops electromagnetic cap to fight Alzheimer's disease

NHS - 19-Sep-2019

Drugs don't work, but the MemorEM cap has shown mental and physical improvements

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New transgenic mouse model with human brain immune cells

New Atlas - 06-Aug-2019

Breakthrough will allow scientists to understand more profoundly how Alzheimer's disease progresses

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Alzheimer's-like disease discovery could mean new targets for treatments

BBC - 30-Apr-2019

Late linked to the accumulation TDP-43 protein rather than amyloid and tau

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Alector raises 133 million to tackle neurodegenerative diseases

Biospace - 25-Jul-2018

Advancing immune-based therapies for alzheimer’s and dementia

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Inhibition of ageing maybe the solution for Alzheimer's

The San Diego Union-Tribune - 19-Jan-2018

Will be successful than drugs targeting specific aspects of Alzheimer's

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