Genes vs. diet: what really drives longevity?

The Conversation (UK) - 17-Oct-2024

New study finds calorie restriction aids longevity, but genetics may hold the ultimate key

Unlocking the Secrets to a Longer Life through Calorie Restriction

Nature - 09-Oct-2024

A major study shows genetics and immunity are key to the lifespan benefits of calorie restriction

Burning calories linked to longer life in mice- could exercise be the key for humans too?

Proceedings of the National Academy of Sciences (PNAS) - 21-Jun-2024

Energy expenditure, not just eating less, lead to 20% longer life in mice

Calorie restriction initially speeds up, then slows down, biological ageing

Live Forever Club - 20-May-2024

Clearly, eating less may not be a straightforward path to slowing ageing

Study reveals surprising telomere loss patterns in calorie restricted humans

Pennsylvania State University (PSU) - 17-Apr-2024

Complexities spark hope for health benefits beyond telomere length

Eating less activates the gene OXR1 which controls brain ageing and lifespan

Buck Institute - 11-Jan-2024

Research sheds light on the benefits of calorie restriction

Eating less, living longer: the positive effects of calorie restriction

International Institute on Ageing (INIA) - 16-Oct-2023

Modest calorie reduction can activate genes for healthy ageing

Calorie restriction and its effect on DNA methylation

Live Forever Club - 03-Mar-2023

Analysis of CALERIE trial shows a slowing down in the pace of ageing, but no immediate reduction in biological age

University of Alabama at Birmingham looking for IF and CR participants for new study

University of Alabama at Birmingham (UAB) - 10-Oct-2022

Will look at whether health and ageing improves with calorie restriction or intermittent fasting

Low-calorie diet during active period of the cycle increased lifespan in mice

UT Southwestern Medical Center - 05-May-2022

Triple the effect seen over simply restricting calorie intake

Limiting calories rewires immuno-metabolic function for longer healthspan in humans

GEN News - 14-Feb-2022

Protein produced by macrophages was identified as a key player of calorie restriction

Calorie restriction slows age-related stem cell exhaustion, improving overall health

Lifespan.io (LEAF) - 29-Sep-2021

Many studies underlined beneficial effects of calorie restriction in various tissues of mice

Long-term caloric restriction prevents age-related adiposity in aged mice

Lifespan.io (LEAF) - 02-Jul-2021

Targeting SA-T cells: A promising intervention to control age-related chronic diseases

Eating less than 800 calories a day favoured weight loss via hungry pathogens

ScienceAlert - 27-Jun-2021

Long-term safety of the diet is questionable as it alters the healthy gut microbiome

Food odour nullifies lifespan benefits of dietary restriction in nematodes

Lifespan.io (LEAF) - 29-Apr-2021

You may have to avoid smelling, not just eating, food for CR to be effective

A low-calorie diet maintains youthful gut state & improves lifespan

Fight Aging! - 24-Mar-2021

Calorie restriction prevents age-related changes to the gut microbiome in mice

Rapamycin might not be an alternative for calorie restriction

Lifespan.io (LEAF) - 27-Jan-2021

Failed to mimic dietary restriction pathways on extending lifespan in progeroid mice

Extending the healthspan without restricting calorie intake

Medical News Today - 13-Sep-2020

Metabolites vital for pro-longevity effect of calorie restriction can help develop drugs

Double-strand break DNA repair improved in calorie restriction mice

Lifespan.io (LEAF) - 10-Sep-2020

Helps us to understand the mechanism behind CR - and that it has an effect within weeks

Benefits of caloric restriction in intestinal stem cells

Lifespan.io (LEAF) - 05-Aug-2020

One should still consume adequate nutrition while reducing calorie intake

Looking young means you are probably ageing slower

CR VITALITY - 30-Jun-2020

Good genes combined with healthy lifestyle choices can truly make you look younger

Eating less to live longer? Study in fruit fly finds no benefit

Science Daily - 04-Jun-2020

Life extending benefit of dietary restriction might depend upon genetic makeup

Calorie restriction rejuvenates 'brain immune cells' in mice

Fight Aging! - 27-May-2020

Still one of the most reliable interventions when improving long-term health

Autophagy may be the reason behind benefits of calorie restriction

Fight Aging! - 19-Dec-2019

Better to read on best practices of calorie restriction with optimal nutrition before you start

Calorie restriction can restore myelin on demyelinated nerves

Lifespan.io (LEAF) - 22-Nov-2019

Tested in mouse model - but it's a good starting point

Growth Differentiation Factor 11 - beneficial effects in mouse model

Science Daily - 22-Oct-2019

Would we be able to achieve effects of lifestyle changes by just taking a pill?

Exercising and having calorie restrictions could affect bones

News Medical - 11-Sep-2019

Mice who exercised and ate less also had a decrease in bone quantity due to the cut in calories

Alternate-day fasting can help reduce belly fat and lose weight

Medical Xpress - 27-Aug-2019

ADF does not weaken our immune system like other fasting regimens do

Caloric restriction in humans have health benefits

Irish Times - 19-Aug-2019

This method is already being used to extend the lifespan in lab animals

Irrational starving leads to RED-S in sportspeople

BBC - 09-Dec-2018

Good health should never be the cost of success in sports

Relative Energy Deficiency in Sport caused by under-eating

BBC - 09-Dec-2018

Athletes starving themselves causes hormone and bone problems

Low-calorie diet prevents age-related molecular changes

Medical Xpress - 25-May-2018

Short-term diets may accelerate the manifestation of aging symptoms

CR Leads to Longer Life but Less Grey Matter

Genetic Engineering & Biotechnology News (GEN) - 05-Apr-2018

Reduced-?calorie diet slows ageing in people

Nature - 22-Mar-2018

CR improves intestinal-tissue regeneration after injury

News Medical - 22-Feb-2018

Mechanism Behind Calorie Restriction and Lengthened Lifespan Uncovered

Temple Health - 14-Sep-2017

Calorie restriction extends life of monkeys by 3 years

New Scientist - 17-Jan-2017

Eating less may lead to longer life

Irish Times - 07-Apr-2016

Review of Mechanisms that Slow Aging from Calorie Restriction

Fight Aging! - 06-Jan-2015