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Advanced Glycation End Products (AGEs) News

When high blood sugar doesn’t shorten life: What birds teach us about ageing

Live Forever Club - 21-Mar-2025

Carnivorous birds show more protein damage without higher sugar

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Josh Mitteldorf plans to self-experiment with high dosages of spermidine

Aging Matters - 07-May-2024

Backed by science, this natural compound may be the key to living longer and better.

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Scientists made hair grow faster by supercharging a natural cell cleanup process

Lifespan.io (LEAF) - 02-Feb-2024

They used a drug called rapamycin in mice to boost the cell cleaning (autophagy)

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Mutated mtDNA acts as a molecular target for therapeutic treatments of age related diseases

University of Cologne - 16-Dec-2022

Targeting and eliminating mutated mtDNA by subjecting it to autophagy with rapamycin been successful

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Casma Therapeutics secures $46m to advance ground-breaking therapies

Casma Therapeutics - 15-Nov-2022

Funding will accelerate development of autophagy-based treatments for challenging diseases

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Lento bio to launch anti-glycation drugs targeting anti-aging and presbyopia

Ichor Therapeutics - 06-Jun-2022

Lento Bio research into molecular aging damage by accelerating clinical assets

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The anti-malarial drug chloroquine increases lifespan in male mice

Lifespan.io (LEAF) - 30-May-2022

Chloroquine significantly interferes with the fundamental mechanisms behind autophagy

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Casma Therapeutics raises $50m to boost cellular waste management therapies

FierceBiotech - 10-Sep-2020

Novel autophagy-based approaches target muscular dystrophy and other challenging diseases

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Cellular pathway and mechanism leading to osteoporosis

Lifespan.io (LEAF) - 09-Jun-2020

Confirmed in murine and human cell study, findings can aid development of new treatments

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Casma Therapeutics develops drugs to enhance autophagy

Chemical & Engineering News (C&EN) - 03-May-2018

Their approach addresses enzyme deficiencies, aiming to expand treatments for neurodegeneration

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SRF to develop glucosepane-cleaving antibodies with Spiegel Lab

Lifespan.io (LEAF) - 17-Sep-2017

Anti-glucosepane antibodies may offer new therapies for age-related diseases

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