Mice maintain constant telomere length throughout life
Live Forever Club - 04-Sep-2025This challenges the idea that telomere erosion is the main driver of ageing
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Associate professor
Professor Yehuda Tzfati is an associate professor in the Department of Genetics at the Hebrew University of Jerusalem’s Silberman Institute of Life Sciences. His research focuses on telomere biology—specifically telomere and telomerase structure, regulation, and how defects contribute to human genetic diseases like dyskeratosis congenita, Hoyeraal‑Hreidarsson syndrome, and Coats plus syndrome. His lab produced the "Telomouse" model by introducing a single amino acid change in the RTEL1 helicase to generate mice with human‑length telomeres. He also helped develop NanoTelSeq, a nanopore sequencing method for measuring individual telomere lengths.
Visit website: https://bio.huji.ac.il/en/content/tzfati-yehuda
See alsoDetails last updated 04-Sep-2025
This challenges the idea that telomere erosion is the main driver of ageing